Recent Advancements in Microfluidic Biosensors for Clinical Applications

ABSTRACT The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid and accurate detection of complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, and treatment management. Advan...

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Main Authors: Haiyan Wang, Wenjuan Wu
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:iLabmed
Subjects:
Online Access:https://doi.org/10.1002/ila2.70002
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author Haiyan Wang
Wenjuan Wu
author_facet Haiyan Wang
Wenjuan Wu
author_sort Haiyan Wang
collection DOAJ
description ABSTRACT The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid and accurate detection of complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, and treatment management. Advances in novel biomaterials have led to device integration into wearable and implantable systems for point‐of‐care testing. Here, we review recent advances in microfluidic biosensors for clinical applications in detecting nucleic acids, proteins, metabolites, pathogens, and cellular components. We outline the prospects of integrated devices based on microfluidic biosensors for the analysis of biofluids such as sweat and discuss the remaining challenges facing the clinical application of microfluidic biosensors.
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institution Kabale University
issn 2834-443X
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publishDate 2025-06-01
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spelling doaj-art-86fb1f68191a4c729da96945a5cee00f2025-08-20T03:40:13ZengWileyiLabmed2834-443X2834-44482025-06-013213014010.1002/ila2.70002Recent Advancements in Microfluidic Biosensors for Clinical ApplicationsHaiyan Wang0Wenjuan Wu1Department of Laboratory Medicine Shanghai East Hospital Tongji University School of Medicine Shanghai ChinaDepartment of Laboratory Medicine Shanghai East Hospital Tongji University School of Medicine Shanghai ChinaABSTRACT The combination of low‐consumption microfluidic chips and high‐sensitivity biosensors enables rapid and accurate detection of complex target analytes. This integrated system holds significant potential for applications in disease diagnosis, health monitoring, and treatment management. Advances in novel biomaterials have led to device integration into wearable and implantable systems for point‐of‐care testing. Here, we review recent advances in microfluidic biosensors for clinical applications in detecting nucleic acids, proteins, metabolites, pathogens, and cellular components. We outline the prospects of integrated devices based on microfluidic biosensors for the analysis of biofluids such as sweat and discuss the remaining challenges facing the clinical application of microfluidic biosensors.https://doi.org/10.1002/ila2.70002biosensorsclinical applicationsmicrofluidicpoint‐of‐care testing
spellingShingle Haiyan Wang
Wenjuan Wu
Recent Advancements in Microfluidic Biosensors for Clinical Applications
iLabmed
biosensors
clinical applications
microfluidic
point‐of‐care testing
title Recent Advancements in Microfluidic Biosensors for Clinical Applications
title_full Recent Advancements in Microfluidic Biosensors for Clinical Applications
title_fullStr Recent Advancements in Microfluidic Biosensors for Clinical Applications
title_full_unstemmed Recent Advancements in Microfluidic Biosensors for Clinical Applications
title_short Recent Advancements in Microfluidic Biosensors for Clinical Applications
title_sort recent advancements in microfluidic biosensors for clinical applications
topic biosensors
clinical applications
microfluidic
point‐of‐care testing
url https://doi.org/10.1002/ila2.70002
work_keys_str_mv AT haiyanwang recentadvancementsinmicrofluidicbiosensorsforclinicalapplications
AT wenjuanwu recentadvancementsinmicrofluidicbiosensorsforclinicalapplications