Comparative analysis of left atrial volume and strain parameters in hemodialysis vs. peritoneal dialysis patients using four-dimensional automatic quantification technology
Background Cardiovascular complications remain a leading cause of mortality in patients with end-stage kidney disease undergoing dialysis. This study aimed to evaluate differences in left atrial (LA) structure and function between hemodialysis and peritoneal dialysis patients using four-dimensional...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2025-12-01
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| Series: | Renal Failure |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/0886022X.2025.2485390 |
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| author | Mei Jin Lingxiang Ma Bing Li Xuning Huang Meihua Chen |
| author_facet | Mei Jin Lingxiang Ma Bing Li Xuning Huang Meihua Chen |
| author_sort | Mei Jin |
| collection | DOAJ |
| description | Background Cardiovascular complications remain a leading cause of mortality in patients with end-stage kidney disease undergoing dialysis. This study aimed to evaluate differences in left atrial (LA) structure and function between hemodialysis and peritoneal dialysis patients using four-dimensional automatic left atrial quantification (4D Auto LAQ) technology.Methods This study included 125 patients with end-stage kidney disease, categorized into hemodialysis (n = 69) and peritoneal dialysis (n = 56) groups. Conventional echocardiography and 4D Auto LAQ were used to assess LA volume and strain parameters. Differences between groups were analyzed.Results Hemodialysis patients exhibited significantly larger LA minimum volume, maximum volume, pre-atrial contraction volume, and maximum volume index compared to peritoneal dialysis patients (p < 0.05). Conversely, hemodialysis patients had significantly lower LA reservoir circumferential strain (LASr-c) and conduit circumferential strain (LAScd-c) than peritoneal dialysis patients (p < 0.05). LA ejection fraction (LAEF) correlated positively with LASr-c (r = 0.809). Multivariate regression analysis identified LASr-c as independently associated with dialysis modality and LAEF. Sensitivity analysis confirmed LAEF as an independent determinant of LASr-c.Conclusions Hemodialysis is associated with increased LA volume and impaired LA function compared to peritoneal dialysis. These findings highlight the importance of LA monitoring in dialysis patients to identify early cardiac dysfunction. |
| format | Article |
| id | doaj-art-86f69bd3dada42febface2f19b42faf9 |
| institution | DOAJ |
| issn | 0886-022X 1525-6049 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Renal Failure |
| spelling | doaj-art-86f69bd3dada42febface2f19b42faf92025-08-20T03:17:44ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492025-12-0147110.1080/0886022X.2025.2485390Comparative analysis of left atrial volume and strain parameters in hemodialysis vs. peritoneal dialysis patients using four-dimensional automatic quantification technologyMei Jin0Lingxiang Ma1Bing Li2Xuning Huang3Meihua Chen4Department of Ultrasound Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, P.R. ChinaDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, P.R. ChinaDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, P.R. ChinaDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, P.R. ChinaDepartment of Ultrasound Medicine, The Second Affiliated Hospital of Hainan Medical University, Haikou, P.R. ChinaBackground Cardiovascular complications remain a leading cause of mortality in patients with end-stage kidney disease undergoing dialysis. This study aimed to evaluate differences in left atrial (LA) structure and function between hemodialysis and peritoneal dialysis patients using four-dimensional automatic left atrial quantification (4D Auto LAQ) technology.Methods This study included 125 patients with end-stage kidney disease, categorized into hemodialysis (n = 69) and peritoneal dialysis (n = 56) groups. Conventional echocardiography and 4D Auto LAQ were used to assess LA volume and strain parameters. Differences between groups were analyzed.Results Hemodialysis patients exhibited significantly larger LA minimum volume, maximum volume, pre-atrial contraction volume, and maximum volume index compared to peritoneal dialysis patients (p < 0.05). Conversely, hemodialysis patients had significantly lower LA reservoir circumferential strain (LASr-c) and conduit circumferential strain (LAScd-c) than peritoneal dialysis patients (p < 0.05). LA ejection fraction (LAEF) correlated positively with LASr-c (r = 0.809). Multivariate regression analysis identified LASr-c as independently associated with dialysis modality and LAEF. Sensitivity analysis confirmed LAEF as an independent determinant of LASr-c.Conclusions Hemodialysis is associated with increased LA volume and impaired LA function compared to peritoneal dialysis. These findings highlight the importance of LA monitoring in dialysis patients to identify early cardiac dysfunction.https://www.tandfonline.com/doi/10.1080/0886022X.2025.2485390Left atrial volumeleft atrial strainhemodialysisperitoneal dialysisfour-dimensional automatic quantificationcardiovascular risk in dialysis |
| spellingShingle | Mei Jin Lingxiang Ma Bing Li Xuning Huang Meihua Chen Comparative analysis of left atrial volume and strain parameters in hemodialysis vs. peritoneal dialysis patients using four-dimensional automatic quantification technology Renal Failure Left atrial volume left atrial strain hemodialysis peritoneal dialysis four-dimensional automatic quantification cardiovascular risk in dialysis |
| title | Comparative analysis of left atrial volume and strain parameters in hemodialysis vs. peritoneal dialysis patients using four-dimensional automatic quantification technology |
| title_full | Comparative analysis of left atrial volume and strain parameters in hemodialysis vs. peritoneal dialysis patients using four-dimensional automatic quantification technology |
| title_fullStr | Comparative analysis of left atrial volume and strain parameters in hemodialysis vs. peritoneal dialysis patients using four-dimensional automatic quantification technology |
| title_full_unstemmed | Comparative analysis of left atrial volume and strain parameters in hemodialysis vs. peritoneal dialysis patients using four-dimensional automatic quantification technology |
| title_short | Comparative analysis of left atrial volume and strain parameters in hemodialysis vs. peritoneal dialysis patients using four-dimensional automatic quantification technology |
| title_sort | comparative analysis of left atrial volume and strain parameters in hemodialysis vs peritoneal dialysis patients using four dimensional automatic quantification technology |
| topic | Left atrial volume left atrial strain hemodialysis peritoneal dialysis four-dimensional automatic quantification cardiovascular risk in dialysis |
| url | https://www.tandfonline.com/doi/10.1080/0886022X.2025.2485390 |
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