NK/T-cell bone lymphoma-induced hemophagocytic lymphohistiocytosis: A clinical case report
Hemophagocytic lymphohistiocytosis (HLH) is a severe condition characterized by the secretion of large amounts of inflammatory cytokines. Lymphoma is a major cause of secondary HLH. This report describes the case of a child initially diagnosed with HLH who experienced recurrent episodes after treatm...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-06-01
|
| Series: | Radiology Case Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043325002365 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849768904588525568 |
|---|---|
| author | Zhanrong Zhang, MM Feng Chen, MD |
| author_facet | Zhanrong Zhang, MM Feng Chen, MD |
| author_sort | Zhanrong Zhang, MM |
| collection | DOAJ |
| description | Hemophagocytic lymphohistiocytosis (HLH) is a severe condition characterized by the secretion of large amounts of inflammatory cytokines. Lymphoma is a major cause of secondary HLH. This report describes the case of a child initially diagnosed with HLH who experienced recurrent episodes after treatment. Ten months after the initial diagnosis, a mass was discovered in the right upper limb, and pathology findings confirmed NK/T-cell lymphoma. Based on the patient's medical history, this lymphoma was considered the underlying cause of HLH. Patients diagnosed with lymphoma complicated by HLH have a worse prognosis and shorter survival compared with those without HLH. Early diagnosis and timely symptomatic treatment can significantly improve patient prognosis. |
| format | Article |
| id | doaj-art-86dfece87aaf4e469d0240432bacbbb6 |
| institution | DOAJ |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-86dfece87aaf4e469d0240432bacbbb62025-08-20T03:03:38ZengElsevierRadiology Case Reports1930-04332025-06-012063144314710.1016/j.radcr.2025.03.025NK/T-cell bone lymphoma-induced hemophagocytic lymphohistiocytosis: A clinical case reportZhanrong Zhang, MM0Feng Chen, MD1Hainan General Hospital (Hainan Medical University Hainan Hospital), Haikou, ChinaCorresponding author.; Hainan General Hospital (Hainan Medical University Hainan Hospital), Haikou, ChinaHemophagocytic lymphohistiocytosis (HLH) is a severe condition characterized by the secretion of large amounts of inflammatory cytokines. Lymphoma is a major cause of secondary HLH. This report describes the case of a child initially diagnosed with HLH who experienced recurrent episodes after treatment. Ten months after the initial diagnosis, a mass was discovered in the right upper limb, and pathology findings confirmed NK/T-cell lymphoma. Based on the patient's medical history, this lymphoma was considered the underlying cause of HLH. Patients diagnosed with lymphoma complicated by HLH have a worse prognosis and shorter survival compared with those without HLH. Early diagnosis and timely symptomatic treatment can significantly improve patient prognosis.http://www.sciencedirect.com/science/article/pii/S1930043325002365Hemophagocytic lymphohistiocytosisCase reportNK/T-cell lymphomaBone lymphoma |
| spellingShingle | Zhanrong Zhang, MM Feng Chen, MD NK/T-cell bone lymphoma-induced hemophagocytic lymphohistiocytosis: A clinical case report Radiology Case Reports Hemophagocytic lymphohistiocytosis Case report NK/T-cell lymphoma Bone lymphoma |
| title | NK/T-cell bone lymphoma-induced hemophagocytic lymphohistiocytosis: A clinical case report |
| title_full | NK/T-cell bone lymphoma-induced hemophagocytic lymphohistiocytosis: A clinical case report |
| title_fullStr | NK/T-cell bone lymphoma-induced hemophagocytic lymphohistiocytosis: A clinical case report |
| title_full_unstemmed | NK/T-cell bone lymphoma-induced hemophagocytic lymphohistiocytosis: A clinical case report |
| title_short | NK/T-cell bone lymphoma-induced hemophagocytic lymphohistiocytosis: A clinical case report |
| title_sort | nk t cell bone lymphoma induced hemophagocytic lymphohistiocytosis a clinical case report |
| topic | Hemophagocytic lymphohistiocytosis Case report NK/T-cell lymphoma Bone lymphoma |
| url | http://www.sciencedirect.com/science/article/pii/S1930043325002365 |
| work_keys_str_mv | AT zhanrongzhangmm nktcellbonelymphomainducedhemophagocyticlymphohistiocytosisaclinicalcasereport AT fengchenmd nktcellbonelymphomainducedhemophagocyticlymphohistiocytosisaclinicalcasereport |