Inhibition of lanosterol synthase linking with MAPK/JNK signaling pathway suppresses endometrial cancer
Abstract Endometrial cancer (EC) is a significant health threat to women, with recurrence after treatment posing a major challenge. While abnormal cholesterol metabolism has been implicated in EC progression, the underlying mechanisms remain unclear. In this study, we identified lanosterol synthase...
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Main Authors: | Liangjian Ma, Wunan Huang, Xiaolei Liang, Hongli Li, Wei Yu, Lexin Liu, Yuelin Guan, Chang Liu, Xiangjun Chen, Lidan Hu |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2025-02-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-025-02325-y |
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