Radiofrequency and microwave 3D bioprinting of emulsion gel for dysphagia diets
Abstract Three-dimensional (3D) bioprinting of emulsion gels is expected to achieve a flexible design of dysphagia diets for individuals with difficulty in swallowing. In this study, the 3D bioprinting of emulsion gels have been achieved using radiofrequency (RF) and microwaves (MW). The textural pr...
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Nature Portfolio
2025-07-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-025-06804-1 |
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| author | Shuntaro Tsubaki Ayane Ide Daniel R. Slocombe Oliver Castell Ibrahim Maamoun Noriyuki Igura |
| author_facet | Shuntaro Tsubaki Ayane Ide Daniel R. Slocombe Oliver Castell Ibrahim Maamoun Noriyuki Igura |
| author_sort | Shuntaro Tsubaki |
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| description | Abstract Three-dimensional (3D) bioprinting of emulsion gels is expected to achieve a flexible design of dysphagia diets for individuals with difficulty in swallowing. In this study, the 3D bioprinting of emulsion gels have been achieved using radiofrequency (RF) and microwaves (MW). The textural properties were controlled using different RF and MW frequencies. The structure of an emulsion gel ink was composed of ovalbumin, xanthan gum, MgCl2, Tween 80, and canola oil, satisfying the dysphagia diet criteria. The RF treatment at 200 MHz effectively improved the hardness of the emulsion gel by forming thick fibrous aggregates of ovalbumin and ovotransferrin. A 3D-bioprinting system equipped with LEGO Mindstorm EV3 and RF/MW heating was developed in this study to prepare structured emulsion gels. The properties of the 3D-printed gels were found to be equivalent to those of the gels obtained by batch RF/MW heating, satisfying the standards of textural properties for dysphagia diets. The developed RF/MW 3D-bioprinting of hydrogels can be further applied to products such as artificial or cultured meats. |
| format | Article |
| id | doaj-art-86d9e4971b81452683b7b191c7e2b7fd |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Nature Portfolio |
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| series | Scientific Reports |
| spelling | doaj-art-86d9e4971b81452683b7b191c7e2b7fd2025-08-20T04:02:45ZengNature PortfolioScientific Reports2045-23222025-07-011511910.1038/s41598-025-06804-1Radiofrequency and microwave 3D bioprinting of emulsion gel for dysphagia dietsShuntaro Tsubaki0Ayane Ide1Daniel R. Slocombe2Oliver Castell3Ibrahim Maamoun4Noriyuki Igura5Faculty of Agriculture, Kyushu UniversityGraduate School of Bioresource and Bioenvironmental Sciences, Kyushu UniversitySchool of Engineering, Cardiff UniversitySchool of Pharmacy and Pharmaceutical Sciences, College of Biomedical and Life Sciences, Cardiff UniversityFaculty of Agriculture, Kyushu UniversityFaculty of Agriculture, Kyushu UniversityAbstract Three-dimensional (3D) bioprinting of emulsion gels is expected to achieve a flexible design of dysphagia diets for individuals with difficulty in swallowing. In this study, the 3D bioprinting of emulsion gels have been achieved using radiofrequency (RF) and microwaves (MW). The textural properties were controlled using different RF and MW frequencies. The structure of an emulsion gel ink was composed of ovalbumin, xanthan gum, MgCl2, Tween 80, and canola oil, satisfying the dysphagia diet criteria. The RF treatment at 200 MHz effectively improved the hardness of the emulsion gel by forming thick fibrous aggregates of ovalbumin and ovotransferrin. A 3D-bioprinting system equipped with LEGO Mindstorm EV3 and RF/MW heating was developed in this study to prepare structured emulsion gels. The properties of the 3D-printed gels were found to be equivalent to those of the gels obtained by batch RF/MW heating, satisfying the standards of textural properties for dysphagia diets. The developed RF/MW 3D-bioprinting of hydrogels can be further applied to products such as artificial or cultured meats.https://doi.org/10.1038/s41598-025-06804-1MicrowavesRadiofrequencyEmulsion gelElectric field3D bioprinting |
| spellingShingle | Shuntaro Tsubaki Ayane Ide Daniel R. Slocombe Oliver Castell Ibrahim Maamoun Noriyuki Igura Radiofrequency and microwave 3D bioprinting of emulsion gel for dysphagia diets Scientific Reports Microwaves Radiofrequency Emulsion gel Electric field 3D bioprinting |
| title | Radiofrequency and microwave 3D bioprinting of emulsion gel for dysphagia diets |
| title_full | Radiofrequency and microwave 3D bioprinting of emulsion gel for dysphagia diets |
| title_fullStr | Radiofrequency and microwave 3D bioprinting of emulsion gel for dysphagia diets |
| title_full_unstemmed | Radiofrequency and microwave 3D bioprinting of emulsion gel for dysphagia diets |
| title_short | Radiofrequency and microwave 3D bioprinting of emulsion gel for dysphagia diets |
| title_sort | radiofrequency and microwave 3d bioprinting of emulsion gel for dysphagia diets |
| topic | Microwaves Radiofrequency Emulsion gel Electric field 3D bioprinting |
| url | https://doi.org/10.1038/s41598-025-06804-1 |
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