Small intestinal bacterial overgrowth in patients with chronic hepatitis C
In order to estimate the frequency of detection of bacterial overgrowth syndrome in patients with chronic hepatitis C, find a possible relationship between development dysbiotic changes in the small intestine and over chronic hepatitis C were examined 80 patients (68 males and 12 females). In additi...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2014-09-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/68 |
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| author | K. V. Zhdanov D. A. Gusev S. M. Zacharenko K. V. Kozlov A. S. Sigidayev M. V. Kurtukov V. S. Sukachev |
| author_facet | K. V. Zhdanov D. A. Gusev S. M. Zacharenko K. V. Kozlov A. S. Sigidayev M. V. Kurtukov V. S. Sukachev |
| author_sort | K. V. Zhdanov |
| collection | DOAJ |
| description | In order to estimate the frequency of detection of bacterial overgrowth syndrome in patients with chronic hepatitis C, find a possible relationship between development dysbiotic changes in the small intestine and over chronic hepatitis C were examined 80 patients (68 males and 12 females). In addition to standard laboratory tests for all patients was performed hydrogen breath test with a load of lactulose and fibrogastroduodenoscopy and hepatic biopsy with subsequent histological examination of biopsy. It was found that bacterial overgrowth syndrome, according to the hydrogen breath test detected 40% of patients with chronic hepatitis C, and the severity of it increases with the progression of the pathological process in the liver tissue. urthermore, in patients with endoscopic signs of catarrhal duodenitis according fibrogastroduodenoscopy, the level of molecular hydrogen when the hydrogen breath test at the appropriate stages of measurement was significantly lower, which may be due to the lack of saccharolytic and / or the predominance of proteolytic flora in the development of bacterial overgrowth syndrome. |
| format | Article |
| id | doaj-art-86ca2359ff5c45e5afb8b7466646cb32 |
| institution | Kabale University |
| issn | 2072-6732 |
| language | Russian |
| publishDate | 2014-09-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj-art-86ca2359ff5c45e5afb8b7466646cb322025-08-20T03:44:24ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-01349810110.22625/2072-6732-2011-3-4-98-10182Small intestinal bacterial overgrowth in patients with chronic hepatitis CK. V. Zhdanov0D. A. Gusev1S. M. Zacharenko2K. V. Kozlov3A. S. Sigidayev4M. V. Kurtukov5V. S. Sukachev6Military Medical Academy named after S.M. Kirov, Saint-PetersburgMilitary Medical Academy named after S.M. Kirov, Saint-PetersburgMilitary Medical Academy named after S.M. Kirov, Saint-PetersburgMilitary Medical Academy named after S.M. Kirov, Saint-PetersburgMilitary Medical Academy named after S.M. Kirov, Saint-PetersburgMilitary Medical Academy named after S.M. Kirov, Saint-PetersburgMilitary Medical Academy named after S.M. Kirov, Saint-PetersburgIn order to estimate the frequency of detection of bacterial overgrowth syndrome in patients with chronic hepatitis C, find a possible relationship between development dysbiotic changes in the small intestine and over chronic hepatitis C were examined 80 patients (68 males and 12 females). In addition to standard laboratory tests for all patients was performed hydrogen breath test with a load of lactulose and fibrogastroduodenoscopy and hepatic biopsy with subsequent histological examination of biopsy. It was found that bacterial overgrowth syndrome, according to the hydrogen breath test detected 40% of patients with chronic hepatitis C, and the severity of it increases with the progression of the pathological process in the liver tissue. urthermore, in patients with endoscopic signs of catarrhal duodenitis according fibrogastroduodenoscopy, the level of molecular hydrogen when the hydrogen breath test at the appropriate stages of measurement was significantly lower, which may be due to the lack of saccharolytic and / or the predominance of proteolytic flora in the development of bacterial overgrowth syndrome.https://journal.niidi.ru/jofin/article/view/68small intestinal bacterial overgrowthchronic hepatitis ch2-breath testalthistological activity |
| spellingShingle | K. V. Zhdanov D. A. Gusev S. M. Zacharenko K. V. Kozlov A. S. Sigidayev M. V. Kurtukov V. S. Sukachev Small intestinal bacterial overgrowth in patients with chronic hepatitis C Журнал инфектологии small intestinal bacterial overgrowth chronic hepatitis c h2-breath test alt histological activity |
| title | Small intestinal bacterial overgrowth in patients with chronic hepatitis C |
| title_full | Small intestinal bacterial overgrowth in patients with chronic hepatitis C |
| title_fullStr | Small intestinal bacterial overgrowth in patients with chronic hepatitis C |
| title_full_unstemmed | Small intestinal bacterial overgrowth in patients with chronic hepatitis C |
| title_short | Small intestinal bacterial overgrowth in patients with chronic hepatitis C |
| title_sort | small intestinal bacterial overgrowth in patients with chronic hepatitis c |
| topic | small intestinal bacterial overgrowth chronic hepatitis c h2-breath test alt histological activity |
| url | https://journal.niidi.ru/jofin/article/view/68 |
| work_keys_str_mv | AT kvzhdanov smallintestinalbacterialovergrowthinpatientswithchronichepatitisc AT dagusev smallintestinalbacterialovergrowthinpatientswithchronichepatitisc AT smzacharenko smallintestinalbacterialovergrowthinpatientswithchronichepatitisc AT kvkozlov smallintestinalbacterialovergrowthinpatientswithchronichepatitisc AT assigidayev smallintestinalbacterialovergrowthinpatientswithchronichepatitisc AT mvkurtukov smallintestinalbacterialovergrowthinpatientswithchronichepatitisc AT vssukachev smallintestinalbacterialovergrowthinpatientswithchronichepatitisc |