Neurogasobiology of migraine: Carbon monoxide, hydrogen sulfide, and nitric oxide as emerging pathophysiological trinacrium relevant to nociception regulation
Nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H₂S) are bioactive gasotransmitters implicated in migraine pathophysiology. These gases regulate vascular tone, nociceptive transmission, and inflammatory pathways, playing key roles in both the onset and modulation of migraine.
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
2025-05-01
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| Series: | Open Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1515/med-2025-1201 |
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| Summary: | Nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H₂S) are bioactive gasotransmitters implicated in migraine pathophysiology. These gases regulate vascular tone, nociceptive transmission, and inflammatory pathways, playing key roles in both the onset and modulation of migraine. |
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| ISSN: | 2391-5463 |