Atypical Presentations of Collagenous Gastritis Mimicking Celiac Sprue
Collagenous gastritis has been reported as a rare cause of nausea, diarrhea, weight changes, and early satiety in female patients. Here, we describe two women aged 43 and 71 years who presented with similar symptoms. Gastric biopsies from both individuals showed thickened, irregular subepithelial co...
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2023/4073588 |
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| author | Mark G. Evans Jack P. Guccione Anthony Crymes Xiaodong Li Cary A. Johnson Vishal S. Chandan Yuxin Lu |
| author_facet | Mark G. Evans Jack P. Guccione Anthony Crymes Xiaodong Li Cary A. Johnson Vishal S. Chandan Yuxin Lu |
| author_sort | Mark G. Evans |
| collection | DOAJ |
| description | Collagenous gastritis has been reported as a rare cause of nausea, diarrhea, weight changes, and early satiety in female patients. Here, we describe two women aged 43 and 71 years who presented with similar symptoms. Gastric biopsies from both individuals showed thickened, irregular subepithelial collagen bands (>10 μm). The pathogenesis of collagenous gastritis is poorly understood, but it may be the presenting symptom for many underlying autoimmune conditions. In particular, there is a well-established connection between collagenous disorders of the gastrointestinal tract and celiac sprue, Sjögren syndrome, and lymphocytic colitis; however, none of these conditions had been diagnosed in our patients. The older woman had incidentally discovered hypogammaglobinemia and IgA deficiency, whereas the younger woman suffered from fibromyalgia. Although a gluten-free diet and budesonide have been effective in some cases, there is no standardized therapy for collagenous gastritis. Our patients trialed diet modification and have required no additional medical interventions. |
| format | Article |
| id | doaj-art-86bc2a2ba5ff46ecbd0e12f9c119f3bb |
| institution | Kabale University |
| issn | 2090-6536 |
| language | English |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-86bc2a2ba5ff46ecbd0e12f9c119f3bb2025-08-20T03:37:53ZengWileyCase Reports in Gastrointestinal Medicine2090-65362023-01-01202310.1155/2023/4073588Atypical Presentations of Collagenous Gastritis Mimicking Celiac SprueMark G. Evans0Jack P. Guccione1Anthony Crymes2Xiaodong Li3Cary A. Johnson4Vishal S. Chandan5Yuxin Lu6Caris Life SciencesLos Angeles County Medical Examiner-CoronerDepartment of MedicineKaiser Permanente Redwood City Medical CenterDepartment of Pathology and Laboratory MedicineDepartment of Pathology and Laboratory MedicineCellNetix Pathology and LaboratoriesCollagenous gastritis has been reported as a rare cause of nausea, diarrhea, weight changes, and early satiety in female patients. Here, we describe two women aged 43 and 71 years who presented with similar symptoms. Gastric biopsies from both individuals showed thickened, irregular subepithelial collagen bands (>10 μm). The pathogenesis of collagenous gastritis is poorly understood, but it may be the presenting symptom for many underlying autoimmune conditions. In particular, there is a well-established connection between collagenous disorders of the gastrointestinal tract and celiac sprue, Sjögren syndrome, and lymphocytic colitis; however, none of these conditions had been diagnosed in our patients. The older woman had incidentally discovered hypogammaglobinemia and IgA deficiency, whereas the younger woman suffered from fibromyalgia. Although a gluten-free diet and budesonide have been effective in some cases, there is no standardized therapy for collagenous gastritis. Our patients trialed diet modification and have required no additional medical interventions.http://dx.doi.org/10.1155/2023/4073588 |
| spellingShingle | Mark G. Evans Jack P. Guccione Anthony Crymes Xiaodong Li Cary A. Johnson Vishal S. Chandan Yuxin Lu Atypical Presentations of Collagenous Gastritis Mimicking Celiac Sprue Case Reports in Gastrointestinal Medicine |
| title | Atypical Presentations of Collagenous Gastritis Mimicking Celiac Sprue |
| title_full | Atypical Presentations of Collagenous Gastritis Mimicking Celiac Sprue |
| title_fullStr | Atypical Presentations of Collagenous Gastritis Mimicking Celiac Sprue |
| title_full_unstemmed | Atypical Presentations of Collagenous Gastritis Mimicking Celiac Sprue |
| title_short | Atypical Presentations of Collagenous Gastritis Mimicking Celiac Sprue |
| title_sort | atypical presentations of collagenous gastritis mimicking celiac sprue |
| url | http://dx.doi.org/10.1155/2023/4073588 |
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