Modified High-Flow Nasal Cannula in Young Children with Pneumonia: A 3-year Retrospective Study
Objectives: We aimed to report our 3-year experience in modified HFNC (MHFNC) usage in young children with community-acquired pneumonia in infectious diseases ward and to identify factors associated with MHFNC failure. Materials and Methods: A retrospective, cross-sectional study of pediatric patien...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2018-07-01
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| Series: | Pediatric Respirology and Critical Care Medicine |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/prcm.prcm_2_18 |
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| _version_ | 1850177514563960832 |
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| author | Issaranee Vareesunthorn Aroonwan Preutthipan |
| author_facet | Issaranee Vareesunthorn Aroonwan Preutthipan |
| author_sort | Issaranee Vareesunthorn |
| collection | DOAJ |
| description | Objectives:
We aimed to report our 3-year experience in modified HFNC (MHFNC) usage in young children with community-acquired pneumonia in infectious diseases ward and to identify factors associated with MHFNC failure.
Materials and Methods:
A retrospective, cross-sectional study of pediatric patients, aged <5 years, with community-acquired pneumonia, who were treated with MHFNC at infectious diseases from August 2012 to December 2015 were recruited. MHFNC failure was defined as a need for further respiratory support within 48 h after initiating MHFNC.
Patients:
Ninety-nine patients with community-acquired pneumonia were included in this study.
Setting:
A tertiary care hospital.
Measurements and Results:
Ninety-nine children (median age of 14 months, body weight 8.6 + 3.1 kg) were included. Ninety-two children (93%) were successfully treated with MHFNC and only seven (7%) were in the failure group. The maximal flow was 3 L/kg/min. Lower oxygen saturation (SpO2)/fraction of inspired oxygen (FiO2) ratio (<264) and higher FiO2 requirement were found to be associated with failure. Maximum FiO2 requirement >0.5 had high odds ratios (22.25) to develop MHFNC failure. No serious complication from MHFNC was found.
Conclusions:
MHFNC is a practical respiratory support in young children with pneumonia. SpO2/FiO2 ratio (<264) and FiO2 requirement >0.5 is a risk factor for MHFNC failure. |
| format | Article |
| id | doaj-art-86b9e2b9784148b2a44b3795fb813939 |
| institution | OA Journals |
| issn | 2543-0343 2543-0351 |
| language | English |
| publishDate | 2018-07-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Pediatric Respirology and Critical Care Medicine |
| spelling | doaj-art-86b9e2b9784148b2a44b3795fb8139392025-08-20T02:18:58ZengWolters Kluwer Medknow PublicationsPediatric Respirology and Critical Care Medicine2543-03432543-03512018-07-0123455010.4103/prcm.prcm_2_18Modified High-Flow Nasal Cannula in Young Children with Pneumonia: A 3-year Retrospective StudyIssaranee VareesunthornAroonwan PreutthipanObjectives: We aimed to report our 3-year experience in modified HFNC (MHFNC) usage in young children with community-acquired pneumonia in infectious diseases ward and to identify factors associated with MHFNC failure. Materials and Methods: A retrospective, cross-sectional study of pediatric patients, aged <5 years, with community-acquired pneumonia, who were treated with MHFNC at infectious diseases from August 2012 to December 2015 were recruited. MHFNC failure was defined as a need for further respiratory support within 48 h after initiating MHFNC. Patients: Ninety-nine patients with community-acquired pneumonia were included in this study. Setting: A tertiary care hospital. Measurements and Results: Ninety-nine children (median age of 14 months, body weight 8.6 + 3.1 kg) were included. Ninety-two children (93%) were successfully treated with MHFNC and only seven (7%) were in the failure group. The maximal flow was 3 L/kg/min. Lower oxygen saturation (SpO2)/fraction of inspired oxygen (FiO2) ratio (<264) and higher FiO2 requirement were found to be associated with failure. Maximum FiO2 requirement >0.5 had high odds ratios (22.25) to develop MHFNC failure. No serious complication from MHFNC was found. Conclusions: MHFNC is a practical respiratory support in young children with pneumonia. SpO2/FiO2 ratio (<264) and FiO2 requirement >0.5 is a risk factor for MHFNC failure.https://journals.lww.com/10.4103/prcm.prcm_2_18high-flow nasal cannulahigh-flow nasal cannula failurehypoxemianoninvasive ventilationpneumonia |
| spellingShingle | Issaranee Vareesunthorn Aroonwan Preutthipan Modified High-Flow Nasal Cannula in Young Children with Pneumonia: A 3-year Retrospective Study Pediatric Respirology and Critical Care Medicine high-flow nasal cannula high-flow nasal cannula failure hypoxemia noninvasive ventilation pneumonia |
| title | Modified High-Flow Nasal Cannula in Young Children with Pneumonia: A 3-year Retrospective Study |
| title_full | Modified High-Flow Nasal Cannula in Young Children with Pneumonia: A 3-year Retrospective Study |
| title_fullStr | Modified High-Flow Nasal Cannula in Young Children with Pneumonia: A 3-year Retrospective Study |
| title_full_unstemmed | Modified High-Flow Nasal Cannula in Young Children with Pneumonia: A 3-year Retrospective Study |
| title_short | Modified High-Flow Nasal Cannula in Young Children with Pneumonia: A 3-year Retrospective Study |
| title_sort | modified high flow nasal cannula in young children with pneumonia a 3 year retrospective study |
| topic | high-flow nasal cannula high-flow nasal cannula failure hypoxemia noninvasive ventilation pneumonia |
| url | https://journals.lww.com/10.4103/prcm.prcm_2_18 |
| work_keys_str_mv | AT issaraneevareesunthorn modifiedhighflownasalcannulainyoungchildrenwithpneumoniaa3yearretrospectivestudy AT aroonwanpreutthipan modifiedhighflownasalcannulainyoungchildrenwithpneumoniaa3yearretrospectivestudy |