Case Report: Carcinosarcoma of the common bile duct: a rare case report with literature review
Carcinosarcoma of the common bile duct is an exceedingly rare and highly aggressive malignancy with uncertain therapeutic outcomes. We present a case of a 70-year-old Asian female presenting with progressive jaundice. Contrast-enhanced computed tomography (CT) identified a tumor in the common bile d...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1642467/full |
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| author | Jia-qi Lou Zhi-Wei Hu Kun Liu Ru-La A Hao-Yu Fang |
| author_facet | Jia-qi Lou Zhi-Wei Hu Kun Liu Ru-La A Hao-Yu Fang |
| author_sort | Jia-qi Lou |
| collection | DOAJ |
| description | Carcinosarcoma of the common bile duct is an exceedingly rare and highly aggressive malignancy with uncertain therapeutic outcomes. We present a case of a 70-year-old Asian female presenting with progressive jaundice. Contrast-enhanced computed tomography (CT) identified a tumor in the common bile duct. The patient underwent successful radical pancreaticoduodenectomy, and postoperative histopathological analysis confirmed carcinosarcoma with predominant sarcomatoid differentiation. This report underscores the diagnostic challenges and therapeutic considerations for this rare entity, emphasizing the critical role of pathological confirmation. |
| format | Article |
| id | doaj-art-86b8bd7196924582ad04660dcace3101 |
| institution | Kabale University |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-86b8bd7196924582ad04660dcace31012025-08-20T03:46:45ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-08-011510.3389/fonc.2025.16424671642467Case Report: Carcinosarcoma of the common bile duct: a rare case report with literature reviewJia-qi Lou0Zhi-Wei Hu1Kun Liu2Ru-La A3Hao-Yu Fang4Department of Surgery, Inner Mongolia Medical University, Hohhot, ChinaDepartment of Hepatobiliary Surgery, Inner Mongolia People’s Hospital, Hohhot, ChinaDepartment of Hepatobiliary Surgery, Beijing Friendship Hospital, Capital Medical University, Beijing, ChinaDepartment of Surgery, Inner Mongolia Medical University, Hohhot, ChinaDepartment of Surgery, Inner Mongolia Medical University, Hohhot, ChinaCarcinosarcoma of the common bile duct is an exceedingly rare and highly aggressive malignancy with uncertain therapeutic outcomes. We present a case of a 70-year-old Asian female presenting with progressive jaundice. Contrast-enhanced computed tomography (CT) identified a tumor in the common bile duct. The patient underwent successful radical pancreaticoduodenectomy, and postoperative histopathological analysis confirmed carcinosarcoma with predominant sarcomatoid differentiation. This report underscores the diagnostic challenges and therapeutic considerations for this rare entity, emphasizing the critical role of pathological confirmation.https://www.frontiersin.org/articles/10.3389/fonc.2025.1642467/fullcarcinosarcomacommon bile ductpancreaticoduodenectomysarcomatoid differentiationprognosis |
| spellingShingle | Jia-qi Lou Zhi-Wei Hu Kun Liu Ru-La A Hao-Yu Fang Case Report: Carcinosarcoma of the common bile duct: a rare case report with literature review Frontiers in Oncology carcinosarcoma common bile duct pancreaticoduodenectomy sarcomatoid differentiation prognosis |
| title | Case Report: Carcinosarcoma of the common bile duct: a rare case report with literature review |
| title_full | Case Report: Carcinosarcoma of the common bile duct: a rare case report with literature review |
| title_fullStr | Case Report: Carcinosarcoma of the common bile duct: a rare case report with literature review |
| title_full_unstemmed | Case Report: Carcinosarcoma of the common bile duct: a rare case report with literature review |
| title_short | Case Report: Carcinosarcoma of the common bile duct: a rare case report with literature review |
| title_sort | case report carcinosarcoma of the common bile duct a rare case report with literature review |
| topic | carcinosarcoma common bile duct pancreaticoduodenectomy sarcomatoid differentiation prognosis |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1642467/full |
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