SHIP-AGE: Frailty, renal function, and multi-component primary care in rural Mecklenburg-West Pomerania (MV-FIT)- study protocol.
<h4>Background</h4>Chronic kidney disease (CKD) is a leading risk factor for cardiovascular disease and all-cause mortality among older adults. Mecklenburg-West Pomerania has the highest CKD prevalence in Germany and Europe, however, its impact on frailty prevention strategies in primary...
Saved in:
| Main Authors: | , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0324001 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849433232997613568 |
|---|---|
| author | Maik Gollasch Yulia Komleva Dmitry Tsvetkov Felix Morof Mladen V Tzvetkov Till Ittermann Marcus Vollmer Uta Zahn-Tesch Holger Kock Franziska Schuster Neeltje van den Berg Henry Völzke Stefan Engeli Lieven Kennes Marwan Mannaa |
| author_facet | Maik Gollasch Yulia Komleva Dmitry Tsvetkov Felix Morof Mladen V Tzvetkov Till Ittermann Marcus Vollmer Uta Zahn-Tesch Holger Kock Franziska Schuster Neeltje van den Berg Henry Völzke Stefan Engeli Lieven Kennes Marwan Mannaa |
| author_sort | Maik Gollasch |
| collection | DOAJ |
| description | <h4>Background</h4>Chronic kidney disease (CKD) is a leading risk factor for cardiovascular disease and all-cause mortality among older adults. Mecklenburg-West Pomerania has the highest CKD prevalence in Germany and Europe, however, its impact on frailty prevention strategies in primary care remains poorly understood. The SHIP-AGE/MV-FIT study aims to investigate the role of CKD in frailty incidence.<h4>Methods</h4>The SHIP-AGE/MV-FIT cohort is a prospective, longitudinal, population-based observational study targeting individuals [Formula: see text] 65 years with mGFR >30 mL/min. The cohort will consist of approximately 820 elderly participants who will be monitored over a three-year period. They will undergo a comprehensive, multi-factorial geriatric assessment, along with a structured monitoring and management program aimed at preventing frailty. The program incorporates evidence-based, multi-component care, including physical activity, medication review, nutritional optimization, and fall prevention strategies.<h4>Discussion</h4>SHIP-AGE/MV-FIT will clarify CKD's role in frailty progression and identify mechanisms underlying frailty and pre-frailty. Additionally, the study aims to implement and evaluate multi-component healthcare strategies for frailty and fall prevention, assess patient adherence and quality of life, and explore elderly individuals' experiences with primary care interventions. By integrating SHIP-AGE data with findings from the SHIP (Study of Health in Pomerania) cohorts in our region, this research will contribute to evidence-based strategies for maintaining health, independence, and well-being in aging populations, particularly in rural primary care settings, such as Mecklenburg-West Pomerania. |
| format | Article |
| id | doaj-art-86b11d3b87774a6b831eec44a4bcf0db |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-86b11d3b87774a6b831eec44a4bcf0db2025-08-20T03:27:07ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01206e032400110.1371/journal.pone.0324001SHIP-AGE: Frailty, renal function, and multi-component primary care in rural Mecklenburg-West Pomerania (MV-FIT)- study protocol.Maik GollaschYulia KomlevaDmitry TsvetkovFelix MorofMladen V TzvetkovTill IttermannMarcus VollmerUta Zahn-TeschHolger KockFranziska SchusterNeeltje van den BergHenry VölzkeStefan EngeliLieven KennesMarwan Mannaa<h4>Background</h4>Chronic kidney disease (CKD) is a leading risk factor for cardiovascular disease and all-cause mortality among older adults. Mecklenburg-West Pomerania has the highest CKD prevalence in Germany and Europe, however, its impact on frailty prevention strategies in primary care remains poorly understood. The SHIP-AGE/MV-FIT study aims to investigate the role of CKD in frailty incidence.<h4>Methods</h4>The SHIP-AGE/MV-FIT cohort is a prospective, longitudinal, population-based observational study targeting individuals [Formula: see text] 65 years with mGFR >30 mL/min. The cohort will consist of approximately 820 elderly participants who will be monitored over a three-year period. They will undergo a comprehensive, multi-factorial geriatric assessment, along with a structured monitoring and management program aimed at preventing frailty. The program incorporates evidence-based, multi-component care, including physical activity, medication review, nutritional optimization, and fall prevention strategies.<h4>Discussion</h4>SHIP-AGE/MV-FIT will clarify CKD's role in frailty progression and identify mechanisms underlying frailty and pre-frailty. Additionally, the study aims to implement and evaluate multi-component healthcare strategies for frailty and fall prevention, assess patient adherence and quality of life, and explore elderly individuals' experiences with primary care interventions. By integrating SHIP-AGE data with findings from the SHIP (Study of Health in Pomerania) cohorts in our region, this research will contribute to evidence-based strategies for maintaining health, independence, and well-being in aging populations, particularly in rural primary care settings, such as Mecklenburg-West Pomerania.https://doi.org/10.1371/journal.pone.0324001 |
| spellingShingle | Maik Gollasch Yulia Komleva Dmitry Tsvetkov Felix Morof Mladen V Tzvetkov Till Ittermann Marcus Vollmer Uta Zahn-Tesch Holger Kock Franziska Schuster Neeltje van den Berg Henry Völzke Stefan Engeli Lieven Kennes Marwan Mannaa SHIP-AGE: Frailty, renal function, and multi-component primary care in rural Mecklenburg-West Pomerania (MV-FIT)- study protocol. PLoS ONE |
| title | SHIP-AGE: Frailty, renal function, and multi-component primary care in rural Mecklenburg-West Pomerania (MV-FIT)- study protocol. |
| title_full | SHIP-AGE: Frailty, renal function, and multi-component primary care in rural Mecklenburg-West Pomerania (MV-FIT)- study protocol. |
| title_fullStr | SHIP-AGE: Frailty, renal function, and multi-component primary care in rural Mecklenburg-West Pomerania (MV-FIT)- study protocol. |
| title_full_unstemmed | SHIP-AGE: Frailty, renal function, and multi-component primary care in rural Mecklenburg-West Pomerania (MV-FIT)- study protocol. |
| title_short | SHIP-AGE: Frailty, renal function, and multi-component primary care in rural Mecklenburg-West Pomerania (MV-FIT)- study protocol. |
| title_sort | ship age frailty renal function and multi component primary care in rural mecklenburg west pomerania mv fit study protocol |
| url | https://doi.org/10.1371/journal.pone.0324001 |
| work_keys_str_mv | AT maikgollasch shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT yuliakomleva shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT dmitrytsvetkov shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT felixmorof shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT mladenvtzvetkov shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT tillittermann shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT marcusvollmer shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT utazahntesch shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT holgerkock shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT franziskaschuster shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT neeltjevandenberg shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT henryvolzke shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT stefanengeli shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT lievenkennes shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol AT marwanmannaa shipagefrailtyrenalfunctionandmulticomponentprimarycareinruralmecklenburgwestpomeraniamvfitstudyprotocol |