UCP2 mediates mitochondrial dynamics to induce AgRP neuronal activity

UCP2 mediates mitochondrial dynamics to induce AgRP neuronal activity

Objectives: The hypothalamic agouti-related protein (AgRP)- expressing neurons regulate feeding and whole-body energy homeostasis. A growing body of evidence indicates that changes in mitochondrial dynamics, such as fission and fusion, play a crucial role in regulating AgRP neuronal activity. Howeve...

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Bibliographic Details
Main Authors: Sungho Jin, Nal Ae Yoon, Zhong-Wu Liu, Ciro Menale, Jung Dae Kim, Nadia Diano, Sabrina Diano
Format: Article
Language:English
Published: Elsevier 2025-09-01
Series:Molecular Metabolism
Subjects:
Arcuate nucleus
AgRP
Uncoupling protein
Mitochondria
Online Access:http://www.sciencedirect.com/science/article/pii/S221287782500122X
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