POLYMORPHISM OF THE TP53 GENE IN PATIENTS WITH GASTRIC CANCER IN PROSPECTIVE AND CLINICAL CASE-CONTROL STUDIES

POLYMORPHISM OF THE TP53 GENE IN PATIENTS WITH GASTRIC CANCER IN PROSPECTIVE AND CLINICAL CASE-CONTROL STUDIES

Background. A functionally significant TP53Arg72Pro polymorphism can contribute to the development of gastric cancer (GC).The aim: to study the associations of genotypes and alleles of the TP53Arg72Pro 4 polymorphism with GC and biomarkers of gastric ucosal atrophy in population-based prospective an...

Full description

Saved in:

Bibliographic Details
Main Authors:	A. V. Belkovets, S. A. Kurilovich, V. N. Maksimov, Yu. I. Ragino, L. V. Scherbakova, O. V. Cheremisina, N. V. Cherdyntseva, M. V. Parulikova, M. I. Voevoda
Format:	Article
Language:	Russian
Published:	Russian Academy of Sciences, Tomsk National Research Medical Center 2018-07-01
Series:	Сибирский онкологический журнал
Subjects:	gastric cancer polymorphism apoptosis tp53 pepsinogenes h. pylori
Online Access:	https://www.siboncoj.ru/jour/article/view/762
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Association of TP53 gene codon 72 polymorphism with Helicobacter pylori-positive non-cardia gastric cancer in Vietnam
by: Thi Minh Thi Ha, et al.
Published: (2019-11-01)

Frequency of hyperglycemia and polymorphism of TNF and TP53 genes in patients with acute pancreatitis, chronic pancreatitis, pancreatic cancer
by: I. N. Grigor’eva, et al.
Published: (2022-02-01)

CASES OF DIFFUSE LARGE B-CELL LYMPHOMA WITH FUNCTIONAL INTRON MUTATIONS IN THE TP53 GENE
by: E. N. Voropaeva, et al.
Published: (2020-03-01)

Polymorphisms in TP53, MDM2 Genes and Risk of Renal Cell Carcinoma in a Mongolian Population
by: Ganbayar Batmunkh, et al.
Published: (2025-03-01)

Carnosic acid enhances cisplatin sensitivity and suppresses gastric cancer progression via the TP53/SLC7A11/ALOX12 axis
by: Li Zhou, et al.
Published: (2025-07-01)

In-frame germline TP53 variant impairs p53 oligomerization and predisposes to cancer
by: Lucie Vanikova, et al.
Published: (2025-08-01)

Asynchronous replication of AURKA and TP53 genes in gastric cancer patients and patients with multiple tumors
by: V. V. Tsepenko, et al.
Published: (2019-07-01)

LSD1 is a targetable vulnerability in gastric cancer harboring TP53 frameshift mutations
by: Suzeng Wang, et al.
Published: (2025-02-01)

Association of polymorphism <i>TP53</i> Arg72Pro with radon-induced lung cancer in the Kazakh population
by: O. Bulgakova, et al.
Published: (2019-08-01)

Genomic Differences and Distinct TP53 Mutation Site‐Linked Chemosensitivity in Early‐ and Late‐Onset Gastric Cancer
by: Tomohiro Kamio, et al.
Published: (2025-04-01)

Impact of TP53 mutations on the efficacy of CAR-T cell therapy in cancer
by: Regina Mirgayazova, et al.
Published: (2024-12-01)

Helicobacter pylori infection and serum pepsinogen concentrations in an elderly population representative of Costa Rica
by: Clas Une, et al.
Published: (2022-01-01)

Association of TP73-AS1 gene polymorphisms with the risk and survival of gastric cancer in a Chinese Han Population
by: Wangwang Chen, et al.
Published: (2019-12-01)

Restoration of TP53 strategy via specific nanoparticles for ovarian cancer therapy
by: Menglei Zhang, et al.
Published: (2025-05-01)

CircTP53/USP10/p53 signaling Axis as a Novel Regulator of Progression and Prognosis of Head and Neck Squamous Cell Carcinoma
by: Yin Wang, et al.
Published: (2025-08-01)

Association between ТР53, MDM2 and NQO1 gene polymorphisms and viral load among women with human papillomavirus
by: A.H. AlBosale, et al.
Published: (2022-03-01)

The Association between Single Nucleotide Polymorphisms rs1042522 and rs1642785 in the TP53 gene and Acute Myeloid leukemia in a sample of the Baghdad/ Iraq population
by: Hadeel Hameed Dawood, et al.
Published: (2024-03-01)

The relationship between TP53 Gene Mutation with treatment results in High-Grade Gliomas
by: Bac Thanh Nguyen, et al.
Published: (2024-05-01)

The prevalence of atrophic gastritis of the body of stomach at Krasnoyarsk population over 45 years old
by: V. V. Tsukanov, et al.
Published: (2012-07-01)

Analyzing serological screening of the functional state of gastric mucosa in clinical practice
by: A. V. Belkovets, et al.
Published: (2024-07-01)

Generation of TP53 knock out induced pluripotent stem cell using CRISPR/Cas9
by: Haonan Zhou, et al.
Published: (2025-06-01)

Identification and prognostic analysis of metabolic genes associated with TP53 mutation in multiple myeloma
by: Xiaoyan Tang, et al.
Published: (2024-12-01)

Osimertinib plus chemotherapy versus osimertinib for patients with advanced NSCLC with concomitant EGFR and TP53 mutations: a prospective cohort study
by: Jixian Li, et al.
Published: (2025-07-01)

Serum Assay Findings after Successful Helicobacter pylori Eradication
by: Sun-Young Lee
Published: (2021-12-01)

Machine learning-based ultrasound radiomics for predicting TP53 mutation status in hepatocellular carcinoma
by: Didi Bu, et al.
Published: (2025-04-01)

The Critical Role of TP53 in Developing Leukaemia in Human and Dogs, Review Article
by: ِAoula Al-Zebeeby, et al.
Published: (2025-06-01)

Insights into an uncommon case: axillary extramammary Paget’s disease and TP53 mutation
by: Julia Zawistowska, et al.
Published: (2025-01-01)

Iron overload mediates cytarabine resistance in AML by inhibiting the TP53 signaling pathway
by: Jia Yan, et al.
Published: (2025-02-01)

Concomitant ALK Fusion and TP53/EGFR Mutation Lead to Adverse Prognostic Outcome
by: Mingyuan Du, et al.
Published: (2024-12-01)

Exploring the role of splicing in TP53 variant pathogenicity through predictions and minigene assays
by: Cristina Fortuno, et al.
Published: (2025-01-01)

Assessing germline TP53 mutations in cancer patients: insights into Li-Fraumeni syndrome and genetic testing guidelines
by: Anastasiia Danishevich, et al.
Published: (2025-02-01)

TERT-TP53 mutations: a novel biomarker pair for hepatocellular carcinoma recurrence and prognosis
by: Jin Li, et al.
Published: (2025-01-01)

Variation characteristics and clinical significance of TP53 in patients with myeloid neoplasms
by: Qiang Ma, et al.
Published: (2024-12-01)

A study on the effect of Helicobacter pylori infection on p53 expression in gastric cancer and gastritis tissues
by: Barik A Salih, et al.
Published: (2013-09-01)

Plasma ctDNA TP53 Mutation and Breast Cancer Prognosis: A Systematic Review and Meta-Analysis
by: FAN Hao, et al.
Published: (2025-07-01)

FKBP10 expression and TP53 mutation predict prognosis and chemotherapy response in triple-negative breast cancer
by: Yan Li, et al.
Published: (2025-07-01)

Deep learning algorithm on H&E whole slide images to characterize TP53 alterations frequency and spatial distribution in breast cancer
by: Chiara Frascarelli, et al.
Published: (2024-12-01)

Elucidating the immune landscape and potential prognostic model in acute myeloid leukemia with TP53 mutation
by: Gelan Zhu, et al.
Published: (2024-12-01)

Hp eradication decreased the expression level of PG II in patients of Hp negative with gastric intestinal metaplasia: a retrospective cross-sectional study
by: Yanhong Wang, et al.
Published: (2025-01-01)

<i>TP53</i> Mutations in Chagasic Megaesophagus
by: Aparecida Perpetuo Fedossi Silveira, et al.
Published: (2025-03-01)