Inactive Graves’ orbitopathy: to treat or not to treat?
Purpose: to evaluate the expediency and efficacy of conservative therapy of patients with inactive stages of Graves’ orbitopathy complicated by optical neuropathy. Materials and methods. 62 patients with an inactive stage of Graves’ orbitopathy complicated by optical neuropathy were divided into two...
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| Format: | Article |
| Language: | Russian |
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Real Time Ltd
2023-03-01
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| Series: | Российский офтальмологический журнал |
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| Online Access: | https://roj.igb.ru/jour/article/view/1169 |
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| author | O. G. Panteleeva F. H. Batyrbekova |
| author_facet | O. G. Panteleeva F. H. Batyrbekova |
| author_sort | O. G. Panteleeva |
| collection | DOAJ |
| description | Purpose: to evaluate the expediency and efficacy of conservative therapy of patients with inactive stages of Graves’ orbitopathy complicated by optical neuropathy. Materials and methods. 62 patients with an inactive stage of Graves’ orbitopathy complicated by optical neuropathy were divided into two groups: group 1 (21 patients, 33.9%) received only symptomatic and local therapy, while group 2 (41 patients, 66.1%) additionally received periorbital injections of glucocorticoid drugs. The patients were examined clinically and instrumentally before and after treatment as well as after a long period of more than 12 months. Results. A positive clinical effect of treatment confirmed by positive dynamics of functional indices of computer perimetry (MS, MD) was achieved in 44 cases (71%), of which 33 patients (75.0% ) belonged to group 2. Positive changes in group 1 were achieved in 52.4% of cases and in group 2 in 80.5% of patients. Long-term results showed stable positive changes in 92.1% of cases. Conclusion. The need for complex therapy, involving local injections of glucocorticoid drugs, of patients in an inactive stage of Grave’s orbitopathy who develop symptoms of optical neuropathy was substantiated. |
| format | Article |
| id | doaj-art-86a25a9fb5a048abb9249118d908fa1f |
| institution | DOAJ |
| issn | 2072-0076 2587-5760 |
| language | Russian |
| publishDate | 2023-03-01 |
| publisher | Real Time Ltd |
| record_format | Article |
| series | Российский офтальмологический журнал |
| spelling | doaj-art-86a25a9fb5a048abb9249118d908fa1f2025-08-20T03:19:24ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602023-03-01161596410.21516/2072-0076-2023-16-1-59-64549Inactive Graves’ orbitopathy: to treat or not to treat?O. G. Panteleeva0F. H. Batyrbekova1Helmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesPurpose: to evaluate the expediency and efficacy of conservative therapy of patients with inactive stages of Graves’ orbitopathy complicated by optical neuropathy. Materials and methods. 62 patients with an inactive stage of Graves’ orbitopathy complicated by optical neuropathy were divided into two groups: group 1 (21 patients, 33.9%) received only symptomatic and local therapy, while group 2 (41 patients, 66.1%) additionally received periorbital injections of glucocorticoid drugs. The patients were examined clinically and instrumentally before and after treatment as well as after a long period of more than 12 months. Results. A positive clinical effect of treatment confirmed by positive dynamics of functional indices of computer perimetry (MS, MD) was achieved in 44 cases (71%), of which 33 patients (75.0% ) belonged to group 2. Positive changes in group 1 were achieved in 52.4% of cases and in group 2 in 80.5% of patients. Long-term results showed stable positive changes in 92.1% of cases. Conclusion. The need for complex therapy, involving local injections of glucocorticoid drugs, of patients in an inactive stage of Grave’s orbitopathy who develop symptoms of optical neuropathy was substantiated.https://roj.igb.ru/jour/article/view/1169graves’ orbitopathythyroid-related ophthalmopathycomputer perimetrythyrotoxicosisglucocorticoids |
| spellingShingle | O. G. Panteleeva F. H. Batyrbekova Inactive Graves’ orbitopathy: to treat or not to treat? Российский офтальмологический журнал graves’ orbitopathy thyroid-related ophthalmopathy computer perimetry thyrotoxicosis glucocorticoids |
| title | Inactive Graves’ orbitopathy: to treat or not to treat? |
| title_full | Inactive Graves’ orbitopathy: to treat or not to treat? |
| title_fullStr | Inactive Graves’ orbitopathy: to treat or not to treat? |
| title_full_unstemmed | Inactive Graves’ orbitopathy: to treat or not to treat? |
| title_short | Inactive Graves’ orbitopathy: to treat or not to treat? |
| title_sort | inactive graves orbitopathy to treat or not to treat |
| topic | graves’ orbitopathy thyroid-related ophthalmopathy computer perimetry thyrotoxicosis glucocorticoids |
| url | https://roj.igb.ru/jour/article/view/1169 |
| work_keys_str_mv | AT ogpanteleeva inactivegravesorbitopathytotreatornottotreat AT fhbatyrbekova inactivegravesorbitopathytotreatornottotreat |