Development of a lysine biosensor for the dynamic regulation of cadaverine biosynthesis in E. coli

Abstract Background As one of the most promising monomers of biobased polyamides, cadaverine has wide industrial application prospects. However, in microbial cadaverine fermentation with glucose as the sole carbon source, the impaired coordination between precursor (lysine) utilization and cytotoxic...

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Bibliographic Details
Main Authors: Mingjie Li, Haorong Chen, Yukun Chen, Pengyu Chen, Shuchun Liu, Shuwen Liu, Tingyi Wen
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Microbial Cell Factories
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Online Access:https://doi.org/10.1186/s12934-025-02772-3
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