Thyroid Gland Disease as a Comorbid Condition in COPD

Introduction. Chronic obstructive pulmonary disease (COPD) is one of the most common causes of morbidity and mortality worldwide. The disease is characterized by progressive airway inflammation, which not only affects the airways but also has systemic effects that are associated with comorbidities....

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Main Authors: Aziz Gumus, Neslihan Ozcelik, Bilge Yilmaz Kara, Songul Ozyurt, Unal Sahin
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Pulmonary Medicine
Online Access:http://dx.doi.org/10.1155/2021/7479992
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author Aziz Gumus
Neslihan Ozcelik
Bilge Yilmaz Kara
Songul Ozyurt
Unal Sahin
author_facet Aziz Gumus
Neslihan Ozcelik
Bilge Yilmaz Kara
Songul Ozyurt
Unal Sahin
author_sort Aziz Gumus
collection DOAJ
description Introduction. Chronic obstructive pulmonary disease (COPD) is one of the most common causes of morbidity and mortality worldwide. The disease is characterized by progressive airway inflammation, which not only affects the airways but also has systemic effects that are associated with comorbidities. Although comorbid conditions such as hypertension and coronary artery disease are very well-known in COPD patients, diseases of the thyroid gland have not been sufficiently studied. Therefore, thyroid diseases are not considered among the comorbid conditions of COPD. The purpose of this study was to determine the thyroid gland disease (TGD) prevalence in COPD and associated factors. Materials and Method. The study included 309 (297 (96%) male) patients. The patients were subjected to spirometry and thyroid function tests (TFT) in the stable period. The thyroid gland disease they were diagnosed with was recorded after face-to-face meetings and examining their files. Results. The mean age of the patients who were included in the study was 65.9±9.8 (40-90). Thyroid disease was determined in 68 (22%) individuals. There were hypothyroidism in 7 (2%), euthyroidism in 45 (15%), and hyperthyroidism in 16 (%5) patients. No relationship was found between the severity of airflow limitation and the prevalence of TGD. Conclusion. Thyroid abnormalities are commonly observed in COPD. The most frequently encountered TGDs are euthyroid multinodular goiter, euthyroid sick syndrome (ESS), and toxic multinodular goiter.
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issn 2090-1844
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series Pulmonary Medicine
spelling doaj-art-868b95738d8048afaa480147bf45c0962025-08-20T03:37:53ZengWileyPulmonary Medicine2090-18442021-01-01202110.1155/2021/7479992Thyroid Gland Disease as a Comorbid Condition in COPDAziz Gumus0Neslihan Ozcelik1Bilge Yilmaz Kara2Songul Ozyurt3Unal Sahin4Recep Tayyip Erdogan UniversityRecep Tayyip Erdogan UniversityRecep Tayyip Erdogan UniversityRecep Tayyip Erdogan UniversityRecep Tayyip Erdogan UniversityIntroduction. Chronic obstructive pulmonary disease (COPD) is one of the most common causes of morbidity and mortality worldwide. The disease is characterized by progressive airway inflammation, which not only affects the airways but also has systemic effects that are associated with comorbidities. Although comorbid conditions such as hypertension and coronary artery disease are very well-known in COPD patients, diseases of the thyroid gland have not been sufficiently studied. Therefore, thyroid diseases are not considered among the comorbid conditions of COPD. The purpose of this study was to determine the thyroid gland disease (TGD) prevalence in COPD and associated factors. Materials and Method. The study included 309 (297 (96%) male) patients. The patients were subjected to spirometry and thyroid function tests (TFT) in the stable period. The thyroid gland disease they were diagnosed with was recorded after face-to-face meetings and examining their files. Results. The mean age of the patients who were included in the study was 65.9±9.8 (40-90). Thyroid disease was determined in 68 (22%) individuals. There were hypothyroidism in 7 (2%), euthyroidism in 45 (15%), and hyperthyroidism in 16 (%5) patients. No relationship was found between the severity of airflow limitation and the prevalence of TGD. Conclusion. Thyroid abnormalities are commonly observed in COPD. The most frequently encountered TGDs are euthyroid multinodular goiter, euthyroid sick syndrome (ESS), and toxic multinodular goiter.http://dx.doi.org/10.1155/2021/7479992
spellingShingle Aziz Gumus
Neslihan Ozcelik
Bilge Yilmaz Kara
Songul Ozyurt
Unal Sahin
Thyroid Gland Disease as a Comorbid Condition in COPD
Pulmonary Medicine
title Thyroid Gland Disease as a Comorbid Condition in COPD
title_full Thyroid Gland Disease as a Comorbid Condition in COPD
title_fullStr Thyroid Gland Disease as a Comorbid Condition in COPD
title_full_unstemmed Thyroid Gland Disease as a Comorbid Condition in COPD
title_short Thyroid Gland Disease as a Comorbid Condition in COPD
title_sort thyroid gland disease as a comorbid condition in copd
url http://dx.doi.org/10.1155/2021/7479992
work_keys_str_mv AT azizgumus thyroidglanddiseaseasacomorbidconditionincopd
AT neslihanozcelik thyroidglanddiseaseasacomorbidconditionincopd
AT bilgeyilmazkara thyroidglanddiseaseasacomorbidconditionincopd
AT songulozyurt thyroidglanddiseaseasacomorbidconditionincopd
AT unalsahin thyroidglanddiseaseasacomorbidconditionincopd