Challenges and opportunities of predicting overall survival benefit from improvements to recurrence-free survival in stage II/III melanoma: a correlation meta-analysis

Challenges and opportunities of predicting overall survival benefit from improvements to recurrence-free survival in stage II/III melanoma: a correlation meta-analysis

Background: We evaluated the association between treatment effects on recurrence-free survival (RFS) and overall survival (OS) in randomized controlled trials (RCTs) studying resected stage II/III melanoma. Methods: Hazard ratios (HRs) of RFS and OS were obtained from a literature review. Bivariate...

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Bibliographic Details
Main Authors: L. Leung, J.M. Kirkwood, S. Srinivasan, M. Dyer, A. Qian, M.-M. Pourrahmat, E. Kasireddy, J.R. May, A. Moshyk, M. Kurt
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Immuno-Oncology and Technology
Subjects:
surrogate endpoints
melanoma
meta-analysis
survival analysis
immunotherapy
adjuvant
Online Access:http://www.sciencedirect.com/science/article/pii/S2590018825000024
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