Systematic scoping review of the concept of 'genetic identity' and its relevance for germline modification.
EU legislation prohibits clinical trials that modify germ line 'genetic identity'. 'Genetic identity' however, is left undefined. This study aims to identify the use of the term 'genetic identity' in academic literature, and investigate its relevance for debates on gene...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2020-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0228263&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832540056911347712 |
|---|---|
| author | Floor M Goekoop Carla G van El Guy A M Widdershoven Nadza Dzinalija Martina C Cornel Natalie Evans |
| author_facet | Floor M Goekoop Carla G van El Guy A M Widdershoven Nadza Dzinalija Martina C Cornel Natalie Evans |
| author_sort | Floor M Goekoop |
| collection | DOAJ |
| description | EU legislation prohibits clinical trials that modify germ line 'genetic identity'. 'Genetic identity' however, is left undefined. This study aims to identify the use of the term 'genetic identity' in academic literature, and investigate its relevance for debates on genetic modification. A total of 616 articles that contained the term were identified. Content analysis revealed that the term was used in various and contradicting ways and a clear understanding of the term is lacking. This review demonstrates that the EU legislation is open to interpretation, because of the diversity of meaning with which 'genetic identity' is currently used. Because of the diversity of meaning with which 'genetic identity' is used and understood, further reflection is needed. This requires further medical, legal, ethical and social debate and a coordinated response at both a European and a global level. |
| format | Article |
| id | doaj-art-8689bada716e4c35a13ae9a665d458d4 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-8689bada716e4c35a13ae9a665d458d42025-02-05T05:33:04ZengPublic Library of Science (PLoS)PLoS ONE1932-62032020-01-01151e022826310.1371/journal.pone.0228263Systematic scoping review of the concept of 'genetic identity' and its relevance for germline modification.Floor M GoekoopCarla G van ElGuy A M WiddershovenNadza DzinalijaMartina C CornelNatalie EvansEU legislation prohibits clinical trials that modify germ line 'genetic identity'. 'Genetic identity' however, is left undefined. This study aims to identify the use of the term 'genetic identity' in academic literature, and investigate its relevance for debates on genetic modification. A total of 616 articles that contained the term were identified. Content analysis revealed that the term was used in various and contradicting ways and a clear understanding of the term is lacking. This review demonstrates that the EU legislation is open to interpretation, because of the diversity of meaning with which 'genetic identity' is currently used. Because of the diversity of meaning with which 'genetic identity' is used and understood, further reflection is needed. This requires further medical, legal, ethical and social debate and a coordinated response at both a European and a global level.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0228263&type=printable |
| spellingShingle | Floor M Goekoop Carla G van El Guy A M Widdershoven Nadza Dzinalija Martina C Cornel Natalie Evans Systematic scoping review of the concept of 'genetic identity' and its relevance for germline modification. PLoS ONE |
| title | Systematic scoping review of the concept of 'genetic identity' and its relevance for germline modification. |
| title_full | Systematic scoping review of the concept of 'genetic identity' and its relevance for germline modification. |
| title_fullStr | Systematic scoping review of the concept of 'genetic identity' and its relevance for germline modification. |
| title_full_unstemmed | Systematic scoping review of the concept of 'genetic identity' and its relevance for germline modification. |
| title_short | Systematic scoping review of the concept of 'genetic identity' and its relevance for germline modification. |
| title_sort | systematic scoping review of the concept of genetic identity and its relevance for germline modification |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0228263&type=printable |
| work_keys_str_mv | AT floormgoekoop systematicscopingreviewoftheconceptofgeneticidentityanditsrelevanceforgermlinemodification AT carlagvanel systematicscopingreviewoftheconceptofgeneticidentityanditsrelevanceforgermlinemodification AT guyamwiddershoven systematicscopingreviewoftheconceptofgeneticidentityanditsrelevanceforgermlinemodification AT nadzadzinalija systematicscopingreviewoftheconceptofgeneticidentityanditsrelevanceforgermlinemodification AT martinaccornel systematicscopingreviewoftheconceptofgeneticidentityanditsrelevanceforgermlinemodification AT natalieevans systematicscopingreviewoftheconceptofgeneticidentityanditsrelevanceforgermlinemodification |