Comparison of mortality in people with type 2 diabetes between different ethnic groups: Systematic review and meta-analysis of longitudinal studies.
<h4>Aims</h4>Type 2 diabetes (T2D) is more common in certain ethnic groups. This systematic review compares mortality risk between people with T2D from different ethnic groups and includes recent larger studies.<h4>Methods</h4>We searched nine databases using PRISMA guideline...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2025-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0314318 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832540261163466752 |
|---|---|
| author | Umar Ahmed Riaz Chaudhry Rebecca Fortescue Liza Bowen Stephen J Woolford Felicity Knights Derek G Cook Tess Harris Julia Critchley |
| author_facet | Umar Ahmed Riaz Chaudhry Rebecca Fortescue Liza Bowen Stephen J Woolford Felicity Knights Derek G Cook Tess Harris Julia Critchley |
| author_sort | Umar Ahmed Riaz Chaudhry |
| collection | DOAJ |
| description | <h4>Aims</h4>Type 2 diabetes (T2D) is more common in certain ethnic groups. This systematic review compares mortality risk between people with T2D from different ethnic groups and includes recent larger studies.<h4>Methods</h4>We searched nine databases using PRISMA guidelines (PROSPERO CRD42022372542). We included community-based prospective studies among adults with T2D from at least two different ethnicities. Two independent reviewers undertook screening, data extraction and quality assessment using the Newcastle-Ottawa Scale. The primary outcome compared all-cause mortality rates between ethnic groups (hazard ratio (HR) with 95% confidence intervals).<h4>Results</h4>From 30,825 searched records, we included 13 studies (7 meta-analysed), incorporating 573,173 T2D participants; 12 were good quality. Mortality risk was lower amongst people with T2D from South Asian [HR 0.68 (0.65-0.72)], Black [HR 0.82 (0.77-0.87)] and Chinese [HR 0.57 (0.46-0.70)] ethnicity compared to people of White ethnicity. Narrative synthesis corroborated these findings but demonstrated that people of indigenous Māori ethnicity had greater mortality risk compared to European ethnicity.<h4>Conclusions</h4>People with T2D of South Asian, Black and Chinese ethnicity have lower all-cause mortality risk than White ethnicity, with Māori ethnicity having higher mortality risk. Factors explaining mortality differences require further study, including understanding complication risk by ethnicity, to improve diabetes outcomes. |
| format | Article |
| id | doaj-art-86848dda2d8e429fb0860f7dc7b6f776 |
| institution | Kabale University |
| issn | 1932-6203 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-86848dda2d8e429fb0860f7dc7b6f7762025-02-05T05:31:14ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01201e031431810.1371/journal.pone.0314318Comparison of mortality in people with type 2 diabetes between different ethnic groups: Systematic review and meta-analysis of longitudinal studies.Umar Ahmed Riaz ChaudhryRebecca FortescueLiza BowenStephen J WoolfordFelicity KnightsDerek G CookTess HarrisJulia Critchley<h4>Aims</h4>Type 2 diabetes (T2D) is more common in certain ethnic groups. This systematic review compares mortality risk between people with T2D from different ethnic groups and includes recent larger studies.<h4>Methods</h4>We searched nine databases using PRISMA guidelines (PROSPERO CRD42022372542). We included community-based prospective studies among adults with T2D from at least two different ethnicities. Two independent reviewers undertook screening, data extraction and quality assessment using the Newcastle-Ottawa Scale. The primary outcome compared all-cause mortality rates between ethnic groups (hazard ratio (HR) with 95% confidence intervals).<h4>Results</h4>From 30,825 searched records, we included 13 studies (7 meta-analysed), incorporating 573,173 T2D participants; 12 were good quality. Mortality risk was lower amongst people with T2D from South Asian [HR 0.68 (0.65-0.72)], Black [HR 0.82 (0.77-0.87)] and Chinese [HR 0.57 (0.46-0.70)] ethnicity compared to people of White ethnicity. Narrative synthesis corroborated these findings but demonstrated that people of indigenous Māori ethnicity had greater mortality risk compared to European ethnicity.<h4>Conclusions</h4>People with T2D of South Asian, Black and Chinese ethnicity have lower all-cause mortality risk than White ethnicity, with Māori ethnicity having higher mortality risk. Factors explaining mortality differences require further study, including understanding complication risk by ethnicity, to improve diabetes outcomes.https://doi.org/10.1371/journal.pone.0314318 |
| spellingShingle | Umar Ahmed Riaz Chaudhry Rebecca Fortescue Liza Bowen Stephen J Woolford Felicity Knights Derek G Cook Tess Harris Julia Critchley Comparison of mortality in people with type 2 diabetes between different ethnic groups: Systematic review and meta-analysis of longitudinal studies. PLoS ONE |
| title | Comparison of mortality in people with type 2 diabetes between different ethnic groups: Systematic review and meta-analysis of longitudinal studies. |
| title_full | Comparison of mortality in people with type 2 diabetes between different ethnic groups: Systematic review and meta-analysis of longitudinal studies. |
| title_fullStr | Comparison of mortality in people with type 2 diabetes between different ethnic groups: Systematic review and meta-analysis of longitudinal studies. |
| title_full_unstemmed | Comparison of mortality in people with type 2 diabetes between different ethnic groups: Systematic review and meta-analysis of longitudinal studies. |
| title_short | Comparison of mortality in people with type 2 diabetes between different ethnic groups: Systematic review and meta-analysis of longitudinal studies. |
| title_sort | comparison of mortality in people with type 2 diabetes between different ethnic groups systematic review and meta analysis of longitudinal studies |
| url | https://doi.org/10.1371/journal.pone.0314318 |
| work_keys_str_mv | AT umarahmedriazchaudhry comparisonofmortalityinpeoplewithtype2diabetesbetweendifferentethnicgroupssystematicreviewandmetaanalysisoflongitudinalstudies AT rebeccafortescue comparisonofmortalityinpeoplewithtype2diabetesbetweendifferentethnicgroupssystematicreviewandmetaanalysisoflongitudinalstudies AT lizabowen comparisonofmortalityinpeoplewithtype2diabetesbetweendifferentethnicgroupssystematicreviewandmetaanalysisoflongitudinalstudies AT stephenjwoolford comparisonofmortalityinpeoplewithtype2diabetesbetweendifferentethnicgroupssystematicreviewandmetaanalysisoflongitudinalstudies AT felicityknights comparisonofmortalityinpeoplewithtype2diabetesbetweendifferentethnicgroupssystematicreviewandmetaanalysisoflongitudinalstudies AT derekgcook comparisonofmortalityinpeoplewithtype2diabetesbetweendifferentethnicgroupssystematicreviewandmetaanalysisoflongitudinalstudies AT tessharris comparisonofmortalityinpeoplewithtype2diabetesbetweendifferentethnicgroupssystematicreviewandmetaanalysisoflongitudinalstudies AT juliacritchley comparisonofmortalityinpeoplewithtype2diabetesbetweendifferentethnicgroupssystematicreviewandmetaanalysisoflongitudinalstudies |