T cells at the site of autoimmune inflammation show increased potential for trogocytosis.

CD4+ T cells acquire membrane fragments from antigen-presenting-cells via a process termed trogocytosis. Identifying which CD4+ T cells undergo trogocytosis in co-culture with Ag-loaded APC can enrich for antigen-reactive T cells without knowledge of their fine specificity or cytokine-production pro...

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Bibliographic Details
Main Authors: Bettina Haastert, Richard J Mellanby, Stephen M Anderton, Richard A O'Connor
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0081404
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