T cells at the site of autoimmune inflammation show increased potential for trogocytosis.
CD4+ T cells acquire membrane fragments from antigen-presenting-cells via a process termed trogocytosis. Identifying which CD4+ T cells undergo trogocytosis in co-culture with Ag-loaded APC can enrich for antigen-reactive T cells without knowledge of their fine specificity or cytokine-production pro...
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| Main Authors: | Bettina Haastert, Richard J Mellanby, Stephen M Anderton, Richard A O'Connor |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2013-01-01
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| Series: | PLoS ONE |
| Online Access: | https://doi.org/10.1371/journal.pone.0081404 |
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