The Association between Hypertension and Insomnia: A Bidirectional Meta-Analysis of Prospective Cohort Studies
Background. Studies on bidirectional associations between hypertension and insomnia are inconclusive. The purpose of this meta-analysis was to systematically review and summarize the current evidence from epidemiological studies that evaluated this relationship. Materials and Methods. PubMed, Embase...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2022-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2022/4476905 |
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| author | Dingwei Liu Chao Yu Ke Huang Shawn Thomas Wei Yang Song Liu Jie Kuang |
| author_facet | Dingwei Liu Chao Yu Ke Huang Shawn Thomas Wei Yang Song Liu Jie Kuang |
| author_sort | Dingwei Liu |
| collection | DOAJ |
| description | Background. Studies on bidirectional associations between hypertension and insomnia are inconclusive. The purpose of this meta-analysis was to systematically review and summarize the current evidence from epidemiological studies that evaluated this relationship. Materials and Methods. PubMed, Embase, China National Knowledge Infrastructure (CNKI), Wan Fang, and VIP databases were searched for studies published up to May 2021. Prospective cohort studies that reported the relationship between hypertension and insomnia in adults were included. Data were extracted or provided by the authors according to the prevalence rate, incidence rate, unadjusted or adjusted odds ratio (OR), and 95% confidence interval (CI). Heterogeneity was assessed by I2 statistics. ORs were pooled by using random-effects models. Results. A total of 23 prospective studies were identified. Twenty cohort studies recorded OR-adjusted value with the outcome for hypertension (OR = 1.11, 95% CI: 1.07–1.16; I2 = 83.9%), and three cohort studies reported OR-adjusted value with the outcome for insomnia (OR = 1.20, 95%CI: 1.08–1.32; I2 = 35.1%). Subgroup analysis showed that early morning awakening and composite insomnia were significantly associated with hypertension. Conclusions. The result indicates a possible bidirectional association between hypertension and insomnia. Early identification and prevention of insomnia in hypertension patients are needed, and vice versa. |
| format | Article |
| id | doaj-art-8670368ad66a444abc2ba224384677ce |
| institution | Kabale University |
| issn | 2090-0392 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-8670368ad66a444abc2ba224384677ce2025-02-03T05:57:38ZengWileyInternational Journal of Hypertension2090-03922022-01-01202210.1155/2022/4476905The Association between Hypertension and Insomnia: A Bidirectional Meta-Analysis of Prospective Cohort StudiesDingwei Liu0Chao Yu1Ke Huang2Shawn Thomas3Wei Yang4Song Liu5Jie Kuang6Department of GastroenterologyCenter for Prevention and Treatment of Cardiovascular DiseasesThe First Clinical Medical CollegeSchool of Public HealthSchool of Public HealthScience and Technology DepartmentJiangxi Provincial Key Laboratory of Preventive MedicineBackground. Studies on bidirectional associations between hypertension and insomnia are inconclusive. The purpose of this meta-analysis was to systematically review and summarize the current evidence from epidemiological studies that evaluated this relationship. Materials and Methods. PubMed, Embase, China National Knowledge Infrastructure (CNKI), Wan Fang, and VIP databases were searched for studies published up to May 2021. Prospective cohort studies that reported the relationship between hypertension and insomnia in adults were included. Data were extracted or provided by the authors according to the prevalence rate, incidence rate, unadjusted or adjusted odds ratio (OR), and 95% confidence interval (CI). Heterogeneity was assessed by I2 statistics. ORs were pooled by using random-effects models. Results. A total of 23 prospective studies were identified. Twenty cohort studies recorded OR-adjusted value with the outcome for hypertension (OR = 1.11, 95% CI: 1.07–1.16; I2 = 83.9%), and three cohort studies reported OR-adjusted value with the outcome for insomnia (OR = 1.20, 95%CI: 1.08–1.32; I2 = 35.1%). Subgroup analysis showed that early morning awakening and composite insomnia were significantly associated with hypertension. Conclusions. The result indicates a possible bidirectional association between hypertension and insomnia. Early identification and prevention of insomnia in hypertension patients are needed, and vice versa.http://dx.doi.org/10.1155/2022/4476905 |
| spellingShingle | Dingwei Liu Chao Yu Ke Huang Shawn Thomas Wei Yang Song Liu Jie Kuang The Association between Hypertension and Insomnia: A Bidirectional Meta-Analysis of Prospective Cohort Studies International Journal of Hypertension |
| title | The Association between Hypertension and Insomnia: A Bidirectional Meta-Analysis of Prospective Cohort Studies |
| title_full | The Association between Hypertension and Insomnia: A Bidirectional Meta-Analysis of Prospective Cohort Studies |
| title_fullStr | The Association between Hypertension and Insomnia: A Bidirectional Meta-Analysis of Prospective Cohort Studies |
| title_full_unstemmed | The Association between Hypertension and Insomnia: A Bidirectional Meta-Analysis of Prospective Cohort Studies |
| title_short | The Association between Hypertension and Insomnia: A Bidirectional Meta-Analysis of Prospective Cohort Studies |
| title_sort | association between hypertension and insomnia a bidirectional meta analysis of prospective cohort studies |
| url | http://dx.doi.org/10.1155/2022/4476905 |
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