Research progress of GLP-1RAs in the treatment of type 2 diabetes mellitus

Research progress of GLP-1RAs in the treatment of type 2 diabetes mellitus

Glucagon-like peptide-1 (GLP-1) is a 30-amino acid intestinal insulin-stimulating factor, which is mainly secreted by L cells in the distal ileum and colon. It has various physiological functions, such as promoting insulin secretion and synthesis, stimulating β-cell proliferation, inducing islet reg...

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Bibliographic Details
Main Authors: Xu He, Wei Zhao, PeiHang Li, YinJiang Zhang, GuoHua Li, HongYu Su, BiNan Lu, ZongRan Pang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pharmacology
Subjects:
GLP-1
GLP-1RAs
T2DM
glucose
mechanism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2024.1483792/full
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