Patient and Caregiver Perceptions of Airway Clearance Methods Used for Cystic Fibrosis

Introduction. Cystic Fibrosis Foundation guidelines recommend people with CF perform daily airway clearance. This can be difficult for patients, as some find it time consuming or uncomfortable. Data comparing airway clearance methods are limited. We surveyed patients and their families to understand...

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Main Authors: Zoe E. Kienenberger, Tyler O. Farber, Mary E. Teresi, Francesca Milavetz, Sachinkumar B. Singh, Katie Larson Ode, Theodosia Thoma, Rebecca L. Weiner, Kathryn R. Burlage, Anthony J. Fischer
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:Canadian Respiratory Journal
Online Access:http://dx.doi.org/10.1155/2023/1422319
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author Zoe E. Kienenberger
Tyler O. Farber
Mary E. Teresi
Francesca Milavetz
Sachinkumar B. Singh
Katie Larson Ode
Theodosia Thoma
Rebecca L. Weiner
Kathryn R. Burlage
Anthony J. Fischer
author_facet Zoe E. Kienenberger
Tyler O. Farber
Mary E. Teresi
Francesca Milavetz
Sachinkumar B. Singh
Katie Larson Ode
Theodosia Thoma
Rebecca L. Weiner
Kathryn R. Burlage
Anthony J. Fischer
author_sort Zoe E. Kienenberger
collection DOAJ
description Introduction. Cystic Fibrosis Foundation guidelines recommend people with CF perform daily airway clearance. This can be difficult for patients, as some find it time consuming or uncomfortable. Data comparing airway clearance methods are limited. We surveyed patients and their families to understand which methods are preferred and identify obstacles to performing airway clearance. Methods. We designed a REDCap survey and enrolled participants in 2021. Respondents reported information on airway clearance usage, time commitment, and medication use. They rated airway clearance methods for effectiveness, comfort, time commitment, importance, and compatibility with other treatments. The analysis included descriptive statistics and clustering. Results. 60 respondents started and 52 completed the survey. The median patient age was 20 years. Respondents experienced a median of four airway clearance methods in their lifetime, including chest wall oscillation (vest, 92%), manual chest physical therapy (CPT, 88%), forced expiration technique (huff or cough, 77%), and exercise (75%). Past 30-day use was highest for exercise (62%) and vest (57%). The time commitment was generally less than 2 hours daily. Of those eligible for CFTR modulators, 53% reported decreased time commitment to airway clearance after starting treatment. On a scale of 0–100, respondents rated CFTR modulators as their most important treatment (median 99.5), followed by exercise (88). Discussion. Patients and caregivers are familiar with several methods of airway clearance for CF. They report distinct strengths and limitations of each method. Exercise and vest are the most common methods of airway clearance. The use of CFTR modulators may reduce patient-reported time commitment to airway clearance.
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spelling doaj-art-865bb73d63ae43d49f2cd992ddd536d92025-08-20T03:07:11ZengWileyCanadian Respiratory Journal1916-72452023-01-01202310.1155/2023/1422319Patient and Caregiver Perceptions of Airway Clearance Methods Used for Cystic FibrosisZoe E. Kienenberger0Tyler O. Farber1Mary E. Teresi2Francesca Milavetz3Sachinkumar B. Singh4Katie Larson Ode5Theodosia Thoma6Rebecca L. Weiner7Kathryn R. Burlage8Anthony J. Fischer9PediatricsPediatricsPediatricsPediatricsPediatricsPediatricsPediatricsPediatricsDepartment of Physical Therapy and Rehabilitation SciencePediatricsIntroduction. Cystic Fibrosis Foundation guidelines recommend people with CF perform daily airway clearance. This can be difficult for patients, as some find it time consuming or uncomfortable. Data comparing airway clearance methods are limited. We surveyed patients and their families to understand which methods are preferred and identify obstacles to performing airway clearance. Methods. We designed a REDCap survey and enrolled participants in 2021. Respondents reported information on airway clearance usage, time commitment, and medication use. They rated airway clearance methods for effectiveness, comfort, time commitment, importance, and compatibility with other treatments. The analysis included descriptive statistics and clustering. Results. 60 respondents started and 52 completed the survey. The median patient age was 20 years. Respondents experienced a median of four airway clearance methods in their lifetime, including chest wall oscillation (vest, 92%), manual chest physical therapy (CPT, 88%), forced expiration technique (huff or cough, 77%), and exercise (75%). Past 30-day use was highest for exercise (62%) and vest (57%). The time commitment was generally less than 2 hours daily. Of those eligible for CFTR modulators, 53% reported decreased time commitment to airway clearance after starting treatment. On a scale of 0–100, respondents rated CFTR modulators as their most important treatment (median 99.5), followed by exercise (88). Discussion. Patients and caregivers are familiar with several methods of airway clearance for CF. They report distinct strengths and limitations of each method. Exercise and vest are the most common methods of airway clearance. The use of CFTR modulators may reduce patient-reported time commitment to airway clearance.http://dx.doi.org/10.1155/2023/1422319
spellingShingle Zoe E. Kienenberger
Tyler O. Farber
Mary E. Teresi
Francesca Milavetz
Sachinkumar B. Singh
Katie Larson Ode
Theodosia Thoma
Rebecca L. Weiner
Kathryn R. Burlage
Anthony J. Fischer
Patient and Caregiver Perceptions of Airway Clearance Methods Used for Cystic Fibrosis
Canadian Respiratory Journal
title Patient and Caregiver Perceptions of Airway Clearance Methods Used for Cystic Fibrosis
title_full Patient and Caregiver Perceptions of Airway Clearance Methods Used for Cystic Fibrosis
title_fullStr Patient and Caregiver Perceptions of Airway Clearance Methods Used for Cystic Fibrosis
title_full_unstemmed Patient and Caregiver Perceptions of Airway Clearance Methods Used for Cystic Fibrosis
title_short Patient and Caregiver Perceptions of Airway Clearance Methods Used for Cystic Fibrosis
title_sort patient and caregiver perceptions of airway clearance methods used for cystic fibrosis
url http://dx.doi.org/10.1155/2023/1422319
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