Real-world patterns of immunoglobulin replacement therapy for infection prevention in common variable immunodeficiency: a multicenter nationwide study

Real-world patterns of immunoglobulin replacement therapy for infection prevention in common variable immunodeficiency: a multicenter nationwide study

Background and aimsImmunoglobulin replacement therapy (IgRT), administered intravenously (IVIg) or subcutaneously (SCIg), is the cornerstone treatment for patients with Common Variable Immunodeficiency (CVID). Although both modalities demonstrate similar efficacy, SCIg is associated with fewer syste...

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Main Authors: Pedro Moral Moral, Victor Garcia-Bustos, Héctor Balastegui-Martin, Sandra Martínez Mercader, Carmen Bracke, Lourdes Mateu, Xavier Solanich, Arnau Antolí, Juan Luis Carrillo-Linares, Ángel Robles-Marhuenda, Francesc Puchades, Ana Pelaez Ballesta, Nuria López-Osle, Miguel Ángel Torralba-Cabeza, Ana María Bielsa Masdeu, Jorge Gil Niño, Nuria Tornador Gaya, Guillem Pascual Castellanos, Rosario Sánchez-Martínez, José Manuel Barragán-Casas, Andrés González-García, José Luís Patier de la Peña, Daniel López-Wolf, Antonia Mora Rufete, Alba Canovas Mora, Marta Dafne Cabañero-Navalon
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
common variable immunodeficiency (CVID)
immunoglobulin replacement therapy (IGRT)
subcutaneous immunoglobulin (SCIg)
intravenous immunoglobulin (IVIg)
real-world evidence
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1640290/full
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