Biomarker identification for Alzheimer’s disease through integration of comprehensive Mendelian randomization and proteomics data

Abstract Background Alzheimer’s disease (AD) is the main cause of dementia with few effective therapies. We aimed to identify potential plasma biomarkers or drug targets for AD by investigating the causal association between plasma proteins and AD by integrating comprehensive Mendelian randomization...

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Bibliographic Details
Main Authors: Hui Zhan, Davis Cammann, Jeffrey L. Cummings, Xianjun Dong, Jingchun Chen
Format: Article
Language:English
Published: BMC 2025-03-01
Series:Journal of Translational Medicine
Online Access:https://doi.org/10.1186/s12967-025-06317-5
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