Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology.

Measuring protective efficacy and quantifying the impact of drug resistance: A novel malaria chemoprevention trial design and methodology.

<h4>Background</h4>Recently revised WHO guidelines on malaria chemoprevention have opened the door to more tailored implementation. Countries face choices on whether to replace old drugs, target additional age groups, and adapt delivery schedules according to local drug resistance levels...

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Main Authors: Andria Mousa, Gina Cuomo-Dannenburg, Hayley A Thompson, R Matthew Chico, Khalid B Beshir, Colin J Sutherland, David Schellenberg, Roly Gosling, Michael Alifrangis, Emma Filtenborg Hocke, Helle Hansson, Ana Chopo-Pizarro, Wilfred F Mbacham, Innocent M Ali, Mike Chaponda, Cally Roper, Lucy C Okell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-05-01
Series:PLoS Medicine
Online Access:https://journals.plos.org/plosmedicine/article/file?id=10.1371/journal.pmed.1004376&type=printable
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