Assessment of MXD3 Expression as a Predictor of Survival in Lung Squamous Cell Carcinoma
Conclusions: Our findings highlight MXD3 as a promising prognostic biomarker for LUSC, with high MXD3 expression predicting poorer survival outcomes. MXD3 expression level, along with lymph node involvement and methylation status, could serve as independent prognostic indicators for risk stratificat...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-01-01
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| Series: | International Journal of Genomics |
| Online Access: | http://dx.doi.org/10.1155/ijog/7355595 |
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| _version_ | 1850152985276973056 |
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| author | Mingzhi Cao Ning Zhang Tangbing Chen Hong Jiang |
| author_facet | Mingzhi Cao Ning Zhang Tangbing Chen Hong Jiang |
| author_sort | Mingzhi Cao |
| collection | DOAJ |
| description | Conclusions: Our findings highlight MXD3 as a promising prognostic biomarker for LUSC, with high MXD3 expression predicting poorer survival outcomes. MXD3 expression level, along with lymph node involvement and methylation status, could serve as independent prognostic indicators for risk stratification and treatment decision-making in LUSC patients. Further research is warranted to elucidate the underlying mechanisms of MXD3-mediated tumorigenesis and its potential as a therapeutic target in LUSC management. |
| format | Article |
| id | doaj-art-8639507a4d164518808a528d4a2c059a |
| institution | OA Journals |
| issn | 2314-4378 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Genomics |
| spelling | doaj-art-8639507a4d164518808a528d4a2c059a2025-08-20T02:25:50ZengWileyInternational Journal of Genomics2314-43782025-01-01202510.1155/ijog/7355595Assessment of MXD3 Expression as a Predictor of Survival in Lung Squamous Cell CarcinomaMingzhi Cao0Ning Zhang1Tangbing Chen2Hong Jiang3Department of Thoracic SurgeryDepartment of Thoracic SurgeryDepartment of Thoracic SurgeryDepartment of Thoracic SurgeryConclusions: Our findings highlight MXD3 as a promising prognostic biomarker for LUSC, with high MXD3 expression predicting poorer survival outcomes. MXD3 expression level, along with lymph node involvement and methylation status, could serve as independent prognostic indicators for risk stratification and treatment decision-making in LUSC patients. Further research is warranted to elucidate the underlying mechanisms of MXD3-mediated tumorigenesis and its potential as a therapeutic target in LUSC management.http://dx.doi.org/10.1155/ijog/7355595 |
| spellingShingle | Mingzhi Cao Ning Zhang Tangbing Chen Hong Jiang Assessment of MXD3 Expression as a Predictor of Survival in Lung Squamous Cell Carcinoma International Journal of Genomics |
| title | Assessment of MXD3 Expression as a Predictor of Survival in Lung Squamous Cell Carcinoma |
| title_full | Assessment of MXD3 Expression as a Predictor of Survival in Lung Squamous Cell Carcinoma |
| title_fullStr | Assessment of MXD3 Expression as a Predictor of Survival in Lung Squamous Cell Carcinoma |
| title_full_unstemmed | Assessment of MXD3 Expression as a Predictor of Survival in Lung Squamous Cell Carcinoma |
| title_short | Assessment of MXD3 Expression as a Predictor of Survival in Lung Squamous Cell Carcinoma |
| title_sort | assessment of mxd3 expression as a predictor of survival in lung squamous cell carcinoma |
| url | http://dx.doi.org/10.1155/ijog/7355595 |
| work_keys_str_mv | AT mingzhicao assessmentofmxd3expressionasapredictorofsurvivalinlungsquamouscellcarcinoma AT ningzhang assessmentofmxd3expressionasapredictorofsurvivalinlungsquamouscellcarcinoma AT tangbingchen assessmentofmxd3expressionasapredictorofsurvivalinlungsquamouscellcarcinoma AT hongjiang assessmentofmxd3expressionasapredictorofsurvivalinlungsquamouscellcarcinoma |