The Association of Myopia Progression with Changes in Retinal Thickness among Primary School Students with Myopia

Purpose. To observe the relationship between myopia progression and changes in retinal thickness during one year of follow-up among primary school children. Methods. The study included 1161 eyes of 708 myopic children, with 616 (53.06%) right eyes and 545 (46.94%) left eyes. The participants underwe...

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Main Authors: Jing Shang Zhang, Jing Li, Jin Da Wang, Ying Xiong, Kai Cao, Meng Li, Kai Jie Wang, Ying Yan Mao, Jian Ying Liu, Xiu-Hua Wan
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2024/1055700
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author Jing Shang Zhang
Jing Li
Jin Da Wang
Ying Xiong
Kai Cao
Meng Li
Kai Jie Wang
Ying Yan Mao
Jian Ying Liu
Xiu-Hua Wan
author_facet Jing Shang Zhang
Jing Li
Jin Da Wang
Ying Xiong
Kai Cao
Meng Li
Kai Jie Wang
Ying Yan Mao
Jian Ying Liu
Xiu-Hua Wan
author_sort Jing Shang Zhang
collection DOAJ
description Purpose. To observe the relationship between myopia progression and changes in retinal thickness during one year of follow-up among primary school children. Methods. The study included 1161 eyes of 708 myopic children, with 616 (53.06%) right eyes and 545 (46.94%) left eyes. The participants underwent a comprehensive ophthalmic examination, including visual acuity, axial length (AL), autorefraction, and optical coherence tomography (OCT) examination in 2016 and in 2017. An analysis was conducted on the differences in retinal thickness between different genders and between high myopia and nonhigh myopia. Furthermore, the study delved into the correlation between the progression of myopia and the changes of retinal thickness. Results. The average diopter was −1.83 ± 1.29D, average AL was 23.78 ± 0.94 mm, and average foveal thickness was 228.02 ± 23.00 μm. For the inner retina, the median value [the lower quartile value, the upper quartile value] of the foveal thickness was thicker in the high myopia group than the nonhigh myopia group (67 [64; 74] μm vs. 63 [56; 70] μm), while the parafoveal region and perifoveal region were thinner in the high myopia group than the nonhigh myopia group (106 [100; 123] μm vs. 124 [117; 130] μm; 95.0 [93; 102] μm vs. 104 [100; 108] μm). Among all the children with myopia, 67.53% (784/1161) of them have a diopter progression within one year. The AL progression was 95.43% (1108/1161). The retinal thickness of all children has slightly increased in various regions. As the AL of the eye increased and the diopter decreased, the progression degree of inner retinal thickness and full retinal thickness (exclusive of full fovea) decreased. Conclusion. For the school-age myopic children, the inner foveal retinal thickness were thicker in highly myopic students than in the nonhighly myopic students, while the parafoveal and perifoveal retina were thinner in highly myopic students. The inner and full retinal thicknesses of male students were thicker than that of females. The progression of myopia mainly affected the changes of the inner retinal thickness in the one-year follow-up.
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spelling doaj-art-863364be83c64de4a79768ebf2e7bb802024-12-02T08:53:58ZengWileyJournal of Ophthalmology2090-00582024-01-01202410.1155/2024/1055700The Association of Myopia Progression with Changes in Retinal Thickness among Primary School Students with MyopiaJing Shang Zhang0Jing Li1Jin Da Wang2Ying Xiong3Kai Cao4Meng Li5Kai Jie Wang6Ying Yan Mao7Jian Ying Liu8Xiu-Hua Wan9Beijing Tongren Eye CenterBeijing Tongren Eye CenterBeijing Tongren Eye CenterBeijing Tongren Eye CenterBeijing Tongren Eye CenterBeijing Tongren Eye CenterBeijing Tongren Eye CenterBeijing Tongren Eye CenterBeijing Tongren Eye CenterBeijing Tongren Eye CenterPurpose. To observe the relationship between myopia progression and changes in retinal thickness during one year of follow-up among primary school children. Methods. The study included 1161 eyes of 708 myopic children, with 616 (53.06%) right eyes and 545 (46.94%) left eyes. The participants underwent a comprehensive ophthalmic examination, including visual acuity, axial length (AL), autorefraction, and optical coherence tomography (OCT) examination in 2016 and in 2017. An analysis was conducted on the differences in retinal thickness between different genders and between high myopia and nonhigh myopia. Furthermore, the study delved into the correlation between the progression of myopia and the changes of retinal thickness. Results. The average diopter was −1.83 ± 1.29D, average AL was 23.78 ± 0.94 mm, and average foveal thickness was 228.02 ± 23.00 μm. For the inner retina, the median value [the lower quartile value, the upper quartile value] of the foveal thickness was thicker in the high myopia group than the nonhigh myopia group (67 [64; 74] μm vs. 63 [56; 70] μm), while the parafoveal region and perifoveal region were thinner in the high myopia group than the nonhigh myopia group (106 [100; 123] μm vs. 124 [117; 130] μm; 95.0 [93; 102] μm vs. 104 [100; 108] μm). Among all the children with myopia, 67.53% (784/1161) of them have a diopter progression within one year. The AL progression was 95.43% (1108/1161). The retinal thickness of all children has slightly increased in various regions. As the AL of the eye increased and the diopter decreased, the progression degree of inner retinal thickness and full retinal thickness (exclusive of full fovea) decreased. Conclusion. For the school-age myopic children, the inner foveal retinal thickness were thicker in highly myopic students than in the nonhighly myopic students, while the parafoveal and perifoveal retina were thinner in highly myopic students. The inner and full retinal thicknesses of male students were thicker than that of females. The progression of myopia mainly affected the changes of the inner retinal thickness in the one-year follow-up.http://dx.doi.org/10.1155/2024/1055700
spellingShingle Jing Shang Zhang
Jing Li
Jin Da Wang
Ying Xiong
Kai Cao
Meng Li
Kai Jie Wang
Ying Yan Mao
Jian Ying Liu
Xiu-Hua Wan
The Association of Myopia Progression with Changes in Retinal Thickness among Primary School Students with Myopia
Journal of Ophthalmology
title The Association of Myopia Progression with Changes in Retinal Thickness among Primary School Students with Myopia
title_full The Association of Myopia Progression with Changes in Retinal Thickness among Primary School Students with Myopia
title_fullStr The Association of Myopia Progression with Changes in Retinal Thickness among Primary School Students with Myopia
title_full_unstemmed The Association of Myopia Progression with Changes in Retinal Thickness among Primary School Students with Myopia
title_short The Association of Myopia Progression with Changes in Retinal Thickness among Primary School Students with Myopia
title_sort association of myopia progression with changes in retinal thickness among primary school students with myopia
url http://dx.doi.org/10.1155/2024/1055700
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