A deep learning framework deploying segment anything to detect pan-cancer mitotic figures from haematoxylin and eosin-stained slides

Abstract Mitotic activity is an important feature for grading several cancer types. However, counting mitotic figures (cells in division) is a time-consuming and laborious task prone to inter-observer variation. Inaccurate recognition of MFs can lead to incorrect grading and hence potential suboptim...

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Main Authors: Zhuoyan Shen, Mikaël Simard, Douglas Brand, Vanghelita Andrei, Ali Al-Khader, Fatine Oumlil, Katherine Trevers, Thomas Butters, Simon Haefliger, Eleanna Kara, Fernanda Amary, Roberto Tirabosco, Paul Cool, Gary Royle, Maria A. Hawkins, Adrienne M. Flanagan, Charles-Antoine Collins-Fekete
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-024-07398-6
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