Intracellular DNA Damage by Lysine-Acetylene Conjugates
Previously, we reported the design and properties of alkyne C-lysine conjugates, a powerful and tunable family of DNA cleaving reagents. We also reported that, upon photoactivation, these molecules are capable of inducing cancer cells death. To prove that the cell death stems from DNA cleavage by th...
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| Main Authors: | Wang-Yong Yang, Qiang Cao, Catherine Callahan, Catalina Galvis, Qing-Xiang Sang, Igor V. Alabugin |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2010-01-01
|
| Series: | Journal of Nucleic Acids |
| Online Access: | http://dx.doi.org/10.4061/2010/931394 |
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