Antimicrobial activity of cranberry juice (Vaccinium macrocarpon L.) ethanol extract against uropathogenic bacteria
Background: Cranberry fruit (Vaccinium macrocarpon L) contains a mixture of phytochemicals like flavonoids which consist of flavonoids, anthocyanins, proanthocyanidins, catechins, phenolic acids, and triterpenoids, all of which have possible antimicrobial (antibacterial, antifungal and antiviral) a...
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| Format: | Article |
| Language: | English |
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Tripoli University
2025-02-01
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| Series: | Open Veterinary Journal |
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| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=227395 |
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| author | Hayder Kamil Jabbar Al Kaabi Baheeja A. Hmood |
| author_facet | Hayder Kamil Jabbar Al Kaabi Baheeja A. Hmood |
| author_sort | Hayder Kamil Jabbar Al Kaabi |
| collection | DOAJ |
| description | Background:
Cranberry fruit (Vaccinium macrocarpon L) contains a mixture of phytochemicals like flavonoids which consist of flavonoids, anthocyanins, proanthocyanidins, catechins, phenolic acids, and triterpenoids, all of which have possible antimicrobial (antibacterial, antifungal and antiviral) activity.
Aim:
This study aimed to determine the antibacterial effect of the ethanol extract of cranberry juice against uropathogen commonly found in urinary tract infections (UTIs) associated with pregnancy.
Methods:
Cranberry fruits were purchased from local markets and juiced, filtered, and dried. The dried powder was extracted with 70% ethanol for 8-10 days. The bacterial isolates used in this study (Escherichia coli, Proteus vulgaris, Staphylococcus aureus, Enterococcus sp., and Coagulase-Negative Staphylococci (CNS)) were collected from the Maternity and Children Hospital in Al-Diwaniyah City, Iraq. The antibacterial activity of the ethanol extract of cranberry juice was measured using a standard Disc diffusion method. Sterile paper discs were soaked in 20 µL of different concentrations (12.5, 25, 50, and 100 mg/ml) of the extract, placed in Mueller–Hinton agar plates, and inoculated with bacterial cultures adjusted to 0.5 McFarland standards. Amoxicillin (30 µg) was used as a positive control, and 70% ethanol was used as negative control.
Results:
The ethanol solution of cranberry juice displayed a significant (p [Open Vet J 2025; 15(2.000): 813-819] |
| format | Article |
| id | doaj-art-862468a7f6d840699315b985e3aa416d |
| institution | OA Journals |
| issn | 2226-4485 2218-6050 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Tripoli University |
| record_format | Article |
| series | Open Veterinary Journal |
| spelling | doaj-art-862468a7f6d840699315b985e3aa416d2025-08-20T02:16:03ZengTripoli UniversityOpen Veterinary Journal2226-44852218-60502025-02-0115281381910.5455/OVJ.2025.v15.i2.30227395Antimicrobial activity of cranberry juice (Vaccinium macrocarpon L.) ethanol extract against uropathogenic bacteriaHayder Kamil Jabbar Al Kaabi0Baheeja A. Hmood1Basic and medical science department, College of Nursing, University of Al-Qadisiyah, Al-Diwaniyah City, Iraq Basic and medical science department, College of Nursing, University of Al-Qadisiyah, Al-Diwaniyah City, IraqBackground: Cranberry fruit (Vaccinium macrocarpon L) contains a mixture of phytochemicals like flavonoids which consist of flavonoids, anthocyanins, proanthocyanidins, catechins, phenolic acids, and triterpenoids, all of which have possible antimicrobial (antibacterial, antifungal and antiviral) activity. Aim: This study aimed to determine the antibacterial effect of the ethanol extract of cranberry juice against uropathogen commonly found in urinary tract infections (UTIs) associated with pregnancy. Methods: Cranberry fruits were purchased from local markets and juiced, filtered, and dried. The dried powder was extracted with 70% ethanol for 8-10 days. The bacterial isolates used in this study (Escherichia coli, Proteus vulgaris, Staphylococcus aureus, Enterococcus sp., and Coagulase-Negative Staphylococci (CNS)) were collected from the Maternity and Children Hospital in Al-Diwaniyah City, Iraq. The antibacterial activity of the ethanol extract of cranberry juice was measured using a standard Disc diffusion method. Sterile paper discs were soaked in 20 µL of different concentrations (12.5, 25, 50, and 100 mg/ml) of the extract, placed in Mueller–Hinton agar plates, and inoculated with bacterial cultures adjusted to 0.5 McFarland standards. Amoxicillin (30 µg) was used as a positive control, and 70% ethanol was used as negative control. Results: The ethanol solution of cranberry juice displayed a significant (p [Open Vet J 2025; 15(2.000): 813-819]http://www.ejmanager.com/fulltextpdf.php?mno=227395antibacterial activitycranberry juicevaccinium macrocarpon l.urinary tract infections |
| spellingShingle | Hayder Kamil Jabbar Al Kaabi Baheeja A. Hmood Antimicrobial activity of cranberry juice (Vaccinium macrocarpon L.) ethanol extract against uropathogenic bacteria Open Veterinary Journal antibacterial activity cranberry juice vaccinium macrocarpon l. urinary tract infections |
| title | Antimicrobial activity of cranberry juice (Vaccinium macrocarpon L.) ethanol extract against uropathogenic bacteria |
| title_full | Antimicrobial activity of cranberry juice (Vaccinium macrocarpon L.) ethanol extract against uropathogenic bacteria |
| title_fullStr | Antimicrobial activity of cranberry juice (Vaccinium macrocarpon L.) ethanol extract against uropathogenic bacteria |
| title_full_unstemmed | Antimicrobial activity of cranberry juice (Vaccinium macrocarpon L.) ethanol extract against uropathogenic bacteria |
| title_short | Antimicrobial activity of cranberry juice (Vaccinium macrocarpon L.) ethanol extract against uropathogenic bacteria |
| title_sort | antimicrobial activity of cranberry juice vaccinium macrocarpon l ethanol extract against uropathogenic bacteria |
| topic | antibacterial activity cranberry juice vaccinium macrocarpon l. urinary tract infections |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=227395 |
| work_keys_str_mv | AT hayderkamiljabbaralkaabi antimicrobialactivityofcranberryjuicevacciniummacrocarponlethanolextractagainsturopathogenicbacteria AT baheejaahmood antimicrobialactivityofcranberryjuicevacciniummacrocarponlethanolextractagainsturopathogenicbacteria |