Update on Surgical Techniques Best Practices to Optimize Outcomes Following Gel Stent Implantation

Vanessa Vera,1 Arsham Sheybani,2 Joseph F Panarelli,3 Davinder S Grover,4 James Lee,5 Earl Randy Craven,2 Thomas W Samuelson,6 Iqbal Ike K Ahmed7 1Allergan, an AbbVie company, Irvine, CA, USA; 2Washington University School of Medicine, St Louis, MO, USA; 3Department of Ophthalmology, New York Univer...

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Main Authors: Vera V, Sheybani A, Panarelli JF, Grover DS, Lee J, Craven ER, Samuelson TW, Ahmed IIK
Format: Article
Language:English
Published: Dove Medical Press 2025-01-01
Series:Clinical Ophthalmology
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Online Access:https://www.dovepress.com/update-on-surgical-techniques-best-practices-to-optimize-outcomes-foll-peer-reviewed-fulltext-article-OPTH
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author Vera V
Sheybani A
Panarelli JF
Grover DS
Lee J
Craven ER
Samuelson TW
Ahmed IIK
author_facet Vera V
Sheybani A
Panarelli JF
Grover DS
Lee J
Craven ER
Samuelson TW
Ahmed IIK
author_sort Vera V
collection DOAJ
description Vanessa Vera,1 Arsham Sheybani,2 Joseph F Panarelli,3 Davinder S Grover,4 James Lee,5 Earl Randy Craven,2 Thomas W Samuelson,6 Iqbal Ike K Ahmed7 1Allergan, an AbbVie company, Irvine, CA, USA; 2Washington University School of Medicine, St Louis, MO, USA; 3Department of Ophthalmology, New York University Langone Health, New York, NY, USA; 4Glaucoma Associates of Texas, Dallas, TX, USA; 5Colorado Eye Institute, Colorado Springs, CO, USA; 6Minnesota Eye Consultants, University of Minnesota, Minneapolis, MN, USA; 7John Moran Eye Center, University of Utah, Salt Lake City, UT, USACorrespondence: James Lee, Colorado Eye Institute, Colorado Springs, CO, 80924, USA, Email jlee@eyescolorado.comAbstract: The XEN® 45 Glaucoma Treatment System (gel stent; Allergan, an AbbVie company, Irvine, CA, USA) is a minimally invasive bleb-forming surgical device that was originally approved to lower intraocular pressure by diverting the aqueous humor from the anterior chamber to the subconjunctival space (like trabeculectomy) following ab-interno placement. Since approval of the gel stent in multiple countries, the implantation technique has evolved considerably, being performed ab interno or ab externo with open or closed conjunctiva, based on patients’ needs and/or surgeons’ preferences. Additional technical variations that can facilitate gel stent placement and/or improve outcomes have also emerged. This article aims to increase awareness of these developments to facilitate informed decision-making and improve surgical success and outcomes for patients.Keywords: ab interno, ab externo, glaucoma, intraocular pressure, surgical outcomes, XEN
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series Clinical Ophthalmology
spelling doaj-art-860f1409dca94d2f883cdfb96f4a6c162025-02-02T15:59:40ZengDove Medical PressClinical Ophthalmology1177-54832025-01-01Volume 1932534799767Update on Surgical Techniques Best Practices to Optimize Outcomes Following Gel Stent ImplantationVera VSheybani APanarelli JFGrover DSLee JCraven ERSamuelson TWAhmed IIKVanessa Vera,1 Arsham Sheybani,2 Joseph F Panarelli,3 Davinder S Grover,4 James Lee,5 Earl Randy Craven,2 Thomas W Samuelson,6 Iqbal Ike K Ahmed7 1Allergan, an AbbVie company, Irvine, CA, USA; 2Washington University School of Medicine, St Louis, MO, USA; 3Department of Ophthalmology, New York University Langone Health, New York, NY, USA; 4Glaucoma Associates of Texas, Dallas, TX, USA; 5Colorado Eye Institute, Colorado Springs, CO, USA; 6Minnesota Eye Consultants, University of Minnesota, Minneapolis, MN, USA; 7John Moran Eye Center, University of Utah, Salt Lake City, UT, USACorrespondence: James Lee, Colorado Eye Institute, Colorado Springs, CO, 80924, USA, Email jlee@eyescolorado.comAbstract: The XEN® 45 Glaucoma Treatment System (gel stent; Allergan, an AbbVie company, Irvine, CA, USA) is a minimally invasive bleb-forming surgical device that was originally approved to lower intraocular pressure by diverting the aqueous humor from the anterior chamber to the subconjunctival space (like trabeculectomy) following ab-interno placement. Since approval of the gel stent in multiple countries, the implantation technique has evolved considerably, being performed ab interno or ab externo with open or closed conjunctiva, based on patients’ needs and/or surgeons’ preferences. Additional technical variations that can facilitate gel stent placement and/or improve outcomes have also emerged. This article aims to increase awareness of these developments to facilitate informed decision-making and improve surgical success and outcomes for patients.Keywords: ab interno, ab externo, glaucoma, intraocular pressure, surgical outcomes, XENhttps://www.dovepress.com/update-on-surgical-techniques-best-practices-to-optimize-outcomes-foll-peer-reviewed-fulltext-article-OPTHab internoab externoglaucomaintraocular pressuresurgical outcomesxen
spellingShingle Vera V
Sheybani A
Panarelli JF
Grover DS
Lee J
Craven ER
Samuelson TW
Ahmed IIK
Update on Surgical Techniques Best Practices to Optimize Outcomes Following Gel Stent Implantation
Clinical Ophthalmology
ab interno
ab externo
glaucoma
intraocular pressure
surgical outcomes
xen
title Update on Surgical Techniques Best Practices to Optimize Outcomes Following Gel Stent Implantation
title_full Update on Surgical Techniques Best Practices to Optimize Outcomes Following Gel Stent Implantation
title_fullStr Update on Surgical Techniques Best Practices to Optimize Outcomes Following Gel Stent Implantation
title_full_unstemmed Update on Surgical Techniques Best Practices to Optimize Outcomes Following Gel Stent Implantation
title_short Update on Surgical Techniques Best Practices to Optimize Outcomes Following Gel Stent Implantation
title_sort update on surgical techniques best practices to optimize outcomes following gel stent implantation
topic ab interno
ab externo
glaucoma
intraocular pressure
surgical outcomes
xen
url https://www.dovepress.com/update-on-surgical-techniques-best-practices-to-optimize-outcomes-foll-peer-reviewed-fulltext-article-OPTH
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