Perspectives of People with Type 2 Diabetes Mellitus Towards a Decision Aid Assessing Preferences of Glucose-Lowering Drugs: The Dilemma of Choosing

Sonia Roldan Munoz,1 Peter GM Mol,1 Femke de Vries,2 Peter R van Dijk,3 Hans Hillege,4 Douwe Postmus,4 Sieta T de Vries1 1Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; 2Faculty of Beta Science, Vrije Universite...

Full description

Saved in:
Bibliographic Details
Main Authors: Roldan Munoz S, Mol PGM, de Vries F, van Dijk PR, Hillege H, Postmus D, de Vries ST
Format: Article
Language:English
Published: Dove Medical Press 2025-01-01
Series:Patient Preference and Adherence
Subjects:
Online Access:https://www.dovepress.com/perspectives-of-people-with-type-2-diabetes-mellitus-towards-a-decisio-peer-reviewed-fulltext-article-PPA
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832584077477150720
author Roldan Munoz S
Mol PGM
de Vries F
van Dijk PR
Hillege H
Postmus D
de Vries ST
author_facet Roldan Munoz S
Mol PGM
de Vries F
van Dijk PR
Hillege H
Postmus D
de Vries ST
author_sort Roldan Munoz S
collection DOAJ
description Sonia Roldan Munoz,1 Peter GM Mol,1 Femke de Vries,2 Peter R van Dijk,3 Hans Hillege,4 Douwe Postmus,4 Sieta T de Vries1 1Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; 2Faculty of Beta Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; 3Division of Endocrinology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; 4Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, NetherlandsCorrespondence: Sieta T de Vries, Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, Email s.t.de.vries@umcg.nlBackground: Treatment guidelines recommend metformin as initial drug in many people with type 2 diabetes (T2D) and low risk of cardiovascular disease, with the possibility to switch to or add other drug classes. A decision aid (DA) could be useful to incorporate a patient’s preferences in the decision of which drug class to choose. We developed such a DA and assessed the perspectives of people with T2D towards its comprehensibility and usability.Methods: The DA consists of a paper-based leaflet followed by a web-based preference elicitation exercise. The leaflet aims at informing patients about drug characteristics (eg, efficacy, safety). The relative importance of these drug characteristics for each participant are then assessed in a web-based exercise, which results in a ranking of the preferred drug classes. A qualitative study using semi-structured interviews was conducted among Dutch patients with T2D who were or had ever been under pharmacological treatment for T2D. The audio-recorded interviews were transcribed verbatim. Thematic analysis was conducted.Results: Fifteen patients participated (median age 64 years, nine women, and most had T2D > 10 years). Risk of hypoglycaemia was most often the characteristic to which patients attached the highest importance (n=5). A glucagon-like peptide-1-antagonist weekly injection fitted best the preferences of most patients (n=8). The interviews revealed improvements for text, pictograms and figures, and formatting, and increased comprehension of how patients completed the DA. Regarding usability, missing information was identified, as well as patients’ perspectives about the usefulness of the DA and its role in shared-decision making.Conclusion: The DA was considered promising for shared-decision making but further improvements regarding its comprehensibility and usability are needed, for which this study provides clear guidance.Keywords: decision aid, diabetes mellitus, type 2, qualitative research, participant preference
format Article
id doaj-art-8603ed99fd54438aa9e0db1b193a4ec2
institution Kabale University
issn 1177-889X
language English
publishDate 2025-01-01
publisher Dove Medical Press
record_format Article
series Patient Preference and Adherence
spelling doaj-art-8603ed99fd54438aa9e0db1b193a4ec22025-01-27T18:05:34ZengDove Medical PressPatient Preference and Adherence1177-889X2025-01-01Volume 1921523499629Perspectives of People with Type 2 Diabetes Mellitus Towards a Decision Aid Assessing Preferences of Glucose-Lowering Drugs: The Dilemma of ChoosingRoldan Munoz SMol PGMde Vries Fvan Dijk PRHillege HPostmus Dde Vries STSonia Roldan Munoz,1 Peter GM Mol,1 Femke de Vries,2 Peter R van Dijk,3 Hans Hillege,4 Douwe Postmus,4 Sieta T de Vries1 1Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; 2Faculty of Beta Science, Vrije Universiteit Amsterdam, Amsterdam, Netherlands; 3Division of Endocrinology, Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; 4Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, NetherlandsCorrespondence: Sieta T de Vries, Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, Email s.t.de.vries@umcg.nlBackground: Treatment guidelines recommend metformin as initial drug in many people with type 2 diabetes (T2D) and low risk of cardiovascular disease, with the possibility to switch to or add other drug classes. A decision aid (DA) could be useful to incorporate a patient’s preferences in the decision of which drug class to choose. We developed such a DA and assessed the perspectives of people with T2D towards its comprehensibility and usability.Methods: The DA consists of a paper-based leaflet followed by a web-based preference elicitation exercise. The leaflet aims at informing patients about drug characteristics (eg, efficacy, safety). The relative importance of these drug characteristics for each participant are then assessed in a web-based exercise, which results in a ranking of the preferred drug classes. A qualitative study using semi-structured interviews was conducted among Dutch patients with T2D who were or had ever been under pharmacological treatment for T2D. The audio-recorded interviews were transcribed verbatim. Thematic analysis was conducted.Results: Fifteen patients participated (median age 64 years, nine women, and most had T2D > 10 years). Risk of hypoglycaemia was most often the characteristic to which patients attached the highest importance (n=5). A glucagon-like peptide-1-antagonist weekly injection fitted best the preferences of most patients (n=8). The interviews revealed improvements for text, pictograms and figures, and formatting, and increased comprehension of how patients completed the DA. Regarding usability, missing information was identified, as well as patients’ perspectives about the usefulness of the DA and its role in shared-decision making.Conclusion: The DA was considered promising for shared-decision making but further improvements regarding its comprehensibility and usability are needed, for which this study provides clear guidance.Keywords: decision aid, diabetes mellitus, type 2, qualitative research, participant preferencehttps://www.dovepress.com/perspectives-of-people-with-type-2-diabetes-mellitus-towards-a-decisio-peer-reviewed-fulltext-article-PPAdecision aiddiabetes mellitustype 2qualitative researchparticipant preferencequalitative research
spellingShingle Roldan Munoz S
Mol PGM
de Vries F
van Dijk PR
Hillege H
Postmus D
de Vries ST
Perspectives of People with Type 2 Diabetes Mellitus Towards a Decision Aid Assessing Preferences of Glucose-Lowering Drugs: The Dilemma of Choosing
Patient Preference and Adherence
decision aid
diabetes mellitus
type 2
qualitative research
participant preference
qualitative research
title Perspectives of People with Type 2 Diabetes Mellitus Towards a Decision Aid Assessing Preferences of Glucose-Lowering Drugs: The Dilemma of Choosing
title_full Perspectives of People with Type 2 Diabetes Mellitus Towards a Decision Aid Assessing Preferences of Glucose-Lowering Drugs: The Dilemma of Choosing
title_fullStr Perspectives of People with Type 2 Diabetes Mellitus Towards a Decision Aid Assessing Preferences of Glucose-Lowering Drugs: The Dilemma of Choosing
title_full_unstemmed Perspectives of People with Type 2 Diabetes Mellitus Towards a Decision Aid Assessing Preferences of Glucose-Lowering Drugs: The Dilemma of Choosing
title_short Perspectives of People with Type 2 Diabetes Mellitus Towards a Decision Aid Assessing Preferences of Glucose-Lowering Drugs: The Dilemma of Choosing
title_sort perspectives of people with type 2 diabetes mellitus towards a decision aid assessing preferences of glucose lowering drugs the dilemma of choosing
topic decision aid
diabetes mellitus
type 2
qualitative research
participant preference
qualitative research
url https://www.dovepress.com/perspectives-of-people-with-type-2-diabetes-mellitus-towards-a-decisio-peer-reviewed-fulltext-article-PPA
work_keys_str_mv AT roldanmunozs perspectivesofpeoplewithtype2diabetesmellitustowardsadecisionaidassessingpreferencesofglucoseloweringdrugsthedilemmaofchoosing
AT molpgm perspectivesofpeoplewithtype2diabetesmellitustowardsadecisionaidassessingpreferencesofglucoseloweringdrugsthedilemmaofchoosing
AT devriesf perspectivesofpeoplewithtype2diabetesmellitustowardsadecisionaidassessingpreferencesofglucoseloweringdrugsthedilemmaofchoosing
AT vandijkpr perspectivesofpeoplewithtype2diabetesmellitustowardsadecisionaidassessingpreferencesofglucoseloweringdrugsthedilemmaofchoosing
AT hillegeh perspectivesofpeoplewithtype2diabetesmellitustowardsadecisionaidassessingpreferencesofglucoseloweringdrugsthedilemmaofchoosing
AT postmusd perspectivesofpeoplewithtype2diabetesmellitustowardsadecisionaidassessingpreferencesofglucoseloweringdrugsthedilemmaofchoosing
AT devriesst perspectivesofpeoplewithtype2diabetesmellitustowardsadecisionaidassessingpreferencesofglucoseloweringdrugsthedilemmaofchoosing