G1 and G2 variants of apolipoprotein L1 among Central African population in Trypanosoma brucei gambiense endemic rural area

G1 and G2 variants of apolipoprotein L1 among Central African population in Trypanosoma brucei gambiense endemic rural area

Introduction: Apolipoprotein L1 (APOL1) risk variants (G1, G2) are known to enhance the protective ability against human African trypanosomiasis (HAT), in addition to their role in kidney and cardiovascular disease. The effects of these variants on trypanosome infection could differ regionally owin...

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Main Authors: Dominique M Mupepe, Marie-Noelle NL Wameso, Hippolyte N Situakibanza, Pépé M Ekulu, Jean Robert R Makulo, Jean Marie N Kayembe, Agathe B Nkoy, Raggue ZM Mvibudulu, Lambertus P Van den Heuvel, Elena N Levtchenko, Kevin L Karume, Victoire A Bikoumou, Nathan B Buila, Benjamin M Longo, Dieudonné N Mumba, Jean René M’Buyamba-Kabangu
Format: Article
Language:English
Published: The Journal of Infection in Developing Countries 2024-10-01
Series:Journal of Infection in Developing Countries
Subjects:
APOL1 variants
trypanosomiasis
endemic
DR Congo
Online Access:https://jidc.org/index.php/journal/article/view/19495
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