Tiragolumab and TIGIT: pioneering the next era of cancer immunotherapy
Tiragolumab, a monoclonal antibody (mAb) targeting T cell immunoreceptor with Ig and ITIM domains (TIGIT), represents a novel approach in cancer immunotherapy. TIGIT, an immunological checkpoint receptor, suppresses T cell activation and promotes immune evasion in various cancers. By inhibiting TIGI...
Saved in:
| Main Author: | Kosar Ghasemi |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
|
| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2025.1568664/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Promising New Anti‐TIGIT Agents: Stealthy Allies in Cancer Immunotherapy
by: Gatadi Srikanth, et al.
Published: (2025-04-01) -
Enhancing T cell anti-tumor efficacy with a PD1-TIGIT chimeric immune-checkpoint switch receptor
by: Jingjing Zhao, et al.
Published: (2023-12-01) -
Anti-TIGIT therapies: a review of preclinical and clinical efficacy and mechanisms
by: Erin C. Sundstrom, et al.
Published: (2025-07-01) -
Exploring the role of TIGIT in patients with Small Cell Lung Cancer as a novel predictor of prognosis and immunotherapy response
by: Li Liu, et al.
Published: (2025-03-01) -
TIGIT immunosuppressive role in female reproductive system malignant neoplasms: from mechanism to therapy
by: A. U. Khamadyanova, et al.
Published: (2020-04-01)