Innovative nanocarriers: Synthetic and biomimetic strategies for enhanced drug delivery

Effective drug delivery plays a vital role in the treatment of various biomedical conditions. Application of innovative nanocarriers could address issues faced in drug delivery such as poor drug distribution, inefficient penetration across biological barriers, targeting and security. With the develo...

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Bibliographic Details
Main Authors: Runzi Guo, Zhenzhen Zhang, Shuyi Zhang, Tingting Gai, Huizhu Yu, Li Su, Heng Yin, Xiuhui Wang, Yafeng Zhang
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Materials Today Bio
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Online Access:http://www.sciencedirect.com/science/article/pii/S2590006425007501
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Summary:Effective drug delivery plays a vital role in the treatment of various biomedical conditions. Application of innovative nanocarriers could address issues faced in drug delivery such as poor drug distribution, inefficient penetration across biological barriers, targeting and security. With the development of nanotechnology, the preparation approaches, structures and properties of nanocarriers are continuously improving, while the comparison of detailed construction strategies and corresponding innovative application of different nanocarriers for enhanced drug delivery are few. In this review, innovative nanocarriers including synthetic nanocarriers with different shapes and biomimetic nanocarriers inspired by different biological sources are introduced. Moreover, the multi-functionalities and advancements of nanocarriers in drug delivery are intensively discussed. Finally, we outline the current limitations and future perspectives of nanocarriers efforts in drug delivery, with a focus on their key challenges from bench to bedside.
ISSN:2590-0064