Narciclasine enhances cisplatin-induced apoptotic cell death by inducing unfolded protein response-mediated regulation of NOXA and MCL1

Abstract Background Platinum-based chemotherapy is commonly used to treat non-small cell lung cancer (NSCLC); however, innate and acquired resistance is clinically seen in many patients. Hence, a combinatorial approach with novel therapeutic agents to overcome chemoresistance is a promising option f...

Full description

Saved in:
Bibliographic Details
Main Authors: Ji Hae Lee, Seung Hee Seo, Jaegal Shim, Yong-Nyun Kim, Kyungsil Yoon
Format: Article
Language:English
Published: BMC 2025-05-01
Series:Cellular & Molecular Biology Letters
Subjects:
Online Access:https://doi.org/10.1186/s11658-025-00735-5
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items