Omega-3 Supplementation is Effective in Reducing Interleukin-6 Levels After Physical Exercise: A Systematic Review

Not only does physical exercise improve health, it can also trigger inflammation. Therefore, supplementation after exercise is necessary to reduce it. Omega 3 is one of the nutrients that can potentially reduce inflammation. The fundamental however, the mechanism is not well known. This study exami...

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Main Authors: Novadri Ayubi, Junian Cahyanto Wibawa, Mohammed Aljunaid, Joseph Lobo, Cyuzuzo Callixte, Heru Syarli Lesmana
Format: Article
Language:English
Published: University of Baghdad/ Al-Kindy College of Medicine 2025-08-01
Series:مجله كليه طب الكندي
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Online Access:https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/2323
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author Novadri Ayubi
Junian Cahyanto Wibawa
Mohammed Aljunaid
Joseph Lobo
Cyuzuzo Callixte
Heru Syarli Lesmana
author_facet Novadri Ayubi
Junian Cahyanto Wibawa
Mohammed Aljunaid
Joseph Lobo
Cyuzuzo Callixte
Heru Syarli Lesmana
author_sort Novadri Ayubi
collection DOAJ
description Not only does physical exercise improve health, it can also trigger inflammation. Therefore, supplementation after exercise is necessary to reduce it. Omega 3 is one of the nutrients that can potentially reduce inflammation. The fundamental however, the mechanism is not well known. This study examined how omega-3 supplementation while exercise affected IL-6 levels, an inflammatory biomarker. Our systematic review analysis examined interleukin 6, inflammation, and omega 3 papers from Pubmed, Web of Science, and Science Direct during the previous five years. This systematic review assessed nine eligible papers. This research assessed standard operating procedures using PRISMA. Taking omega-3 supplements while working out has been shown to reduce IL-6 levels. IL-6 is reduced by omega-3 supplementation during exercise. So, this can be a recommendation for sportsmen in routine consumption to prevent inflammation during exercise.
format Article
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institution Kabale University
issn 1810-9543
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language English
publishDate 2025-08-01
publisher University of Baghdad/ Al-Kindy College of Medicine
record_format Article
series مجله كليه طب الكندي
spelling doaj-art-85cb978348714d1f8da39cbf59201ccd2025-08-20T03:34:05ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652025-08-0121210.47723/vshm7x27Omega-3 Supplementation is Effective in Reducing Interleukin-6 Levels After Physical Exercise: A Systematic ReviewNovadri Ayubi0https://orcid.org/0000-0002-5196-6636Junian Cahyanto Wibawa1https://orcid.org/0009-0009-2597-5350Mohammed Aljunaid2https://orcid.org/0000-0001-6311-2534Joseph Lobo3https://orcid.org/0000-0002-2553-467XCyuzuzo Callixte4https://orcid.org/0000-0002-9137-5515Heru Syarli Lesmana5https://orcid.org/0000-0003-0036-9716Universitas Negeri Surabaya, Surabaya, IndonesiaSTKIP PGRI Trenggalek, Trenggalek, IndonesiaTaiz University, Taiz, YemenBulacan State University, Malolos, PhilippinesUniversity of Rwanda, Butare, RwandaUniversität Innsbruck, Innsbruck, Austria Not only does physical exercise improve health, it can also trigger inflammation. Therefore, supplementation after exercise is necessary to reduce it. Omega 3 is one of the nutrients that can potentially reduce inflammation. The fundamental however, the mechanism is not well known. This study examined how omega-3 supplementation while exercise affected IL-6 levels, an inflammatory biomarker. Our systematic review analysis examined interleukin 6, inflammation, and omega 3 papers from Pubmed, Web of Science, and Science Direct during the previous five years. This systematic review assessed nine eligible papers. This research assessed standard operating procedures using PRISMA. Taking omega-3 supplements while working out has been shown to reduce IL-6 levels. IL-6 is reduced by omega-3 supplementation during exercise. So, this can be a recommendation for sportsmen in routine consumption to prevent inflammation during exercise. https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/2323Omega 3InflammationExerciseIL-6
spellingShingle Novadri Ayubi
Junian Cahyanto Wibawa
Mohammed Aljunaid
Joseph Lobo
Cyuzuzo Callixte
Heru Syarli Lesmana
Omega-3 Supplementation is Effective in Reducing Interleukin-6 Levels After Physical Exercise: A Systematic Review
مجله كليه طب الكندي
Omega 3
Inflammation
Exercise
IL-6
title Omega-3 Supplementation is Effective in Reducing Interleukin-6 Levels After Physical Exercise: A Systematic Review
title_full Omega-3 Supplementation is Effective in Reducing Interleukin-6 Levels After Physical Exercise: A Systematic Review
title_fullStr Omega-3 Supplementation is Effective in Reducing Interleukin-6 Levels After Physical Exercise: A Systematic Review
title_full_unstemmed Omega-3 Supplementation is Effective in Reducing Interleukin-6 Levels After Physical Exercise: A Systematic Review
title_short Omega-3 Supplementation is Effective in Reducing Interleukin-6 Levels After Physical Exercise: A Systematic Review
title_sort omega 3 supplementation is effective in reducing interleukin 6 levels after physical exercise a systematic review
topic Omega 3
Inflammation
Exercise
IL-6
url https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/2323
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AT mohammedaljunaid omega3supplementationiseffectiveinreducinginterleukin6levelsafterphysicalexerciseasystematicreview
AT josephlobo omega3supplementationiseffectiveinreducinginterleukin6levelsafterphysicalexerciseasystematicreview
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