Treating protracted corneal ulcers with UVA corneal collagen crosslinking: clinical cases
It has recently been proposed to use ultraviolet (UVA) corneal collagen crosslinking as an alternative method of treating bacterial ulcerative lesions of the cornea. Ambivalent results regarding the efficacy and safety of this method of treatment limit its implementation in clinical practice so far....
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| Format: | Article |
| Language: | Russian |
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Real Time Ltd
2021-09-01
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| Series: | Российский офтальмологический журнал |
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| Online Access: | https://roj.igb.ru/jour/article/view/729 |
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| author | E. V. Yani E. N. Iomdina V. V. Pozdniakova V. A. Golikova K. E. Seliverstova |
| author_facet | E. V. Yani E. N. Iomdina V. V. Pozdniakova V. A. Golikova K. E. Seliverstova |
| author_sort | E. V. Yani |
| collection | DOAJ |
| description | It has recently been proposed to use ultraviolet (UVA) corneal collagen crosslinking as an alternative method of treating bacterial ulcerative lesions of the cornea. Ambivalent results regarding the efficacy and safety of this method of treatment limit its implementation in clinical practice so far.The purpose of this work is to analyze three clinical cases involving the use of a new device for local UVA crosslinking in the complex treatment of bacterial corneal protracted-course ulcers with the suspected development of mixed fungal infection.Material and methods. For a dynamic follow-up of patients, we used biomicroscopy with a fluorescein test, photo registration and optical coherence tomography of the anterior part of the eye. Inflammatory changes were assessed using a point scale.Results. 3–5 procedures of local UVA exposure (with instillations of 0.1% riboflavin solution) lasting 3–5 minutes each and given with an interval of 2–4 days ensured stable and fast epithelialization of the cornea and a significant increase in visual acuity in the inflammatory process outcome.Conclusion. The first results of treating bacterial corneal ulcers using a new portable device for local UVA crosslinking have shown its high therapeutic efficiency and good prospects for further use in clinical practice. |
| format | Article |
| id | doaj-art-85cabd86fa484a4caf89791f2a7224fb |
| institution | DOAJ |
| issn | 2072-0076 2587-5760 |
| language | Russian |
| publishDate | 2021-09-01 |
| publisher | Real Time Ltd |
| record_format | Article |
| series | Российский офтальмологический журнал |
| spelling | doaj-art-85cabd86fa484a4caf89791f2a7224fb2025-08-20T03:19:24ZrusReal Time LtdРоссийский офтальмологический журнал2072-00762587-57602021-09-0114310611210.21516/2072-0076-2021-14-3-106-112384Treating protracted corneal ulcers with UVA corneal collagen crosslinking: clinical casesE. V. Yani0E. N. Iomdina1V. V. Pozdniakova2V. A. Golikova3K. E. Seliverstova4Helmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesHelmholtz National Medical Research Center of Eye DiseasesIt has recently been proposed to use ultraviolet (UVA) corneal collagen crosslinking as an alternative method of treating bacterial ulcerative lesions of the cornea. Ambivalent results regarding the efficacy and safety of this method of treatment limit its implementation in clinical practice so far.The purpose of this work is to analyze three clinical cases involving the use of a new device for local UVA crosslinking in the complex treatment of bacterial corneal protracted-course ulcers with the suspected development of mixed fungal infection.Material and methods. For a dynamic follow-up of patients, we used biomicroscopy with a fluorescein test, photo registration and optical coherence tomography of the anterior part of the eye. Inflammatory changes were assessed using a point scale.Results. 3–5 procedures of local UVA exposure (with instillations of 0.1% riboflavin solution) lasting 3–5 minutes each and given with an interval of 2–4 days ensured stable and fast epithelialization of the cornea and a significant increase in visual acuity in the inflammatory process outcome.Conclusion. The first results of treating bacterial corneal ulcers using a new portable device for local UVA crosslinking have shown its high therapeutic efficiency and good prospects for further use in clinical practice.https://roj.igb.ru/jour/article/view/729corneal ulcertreatmentultraviolet crosslinkingdevice for local corneal collagen crosslinking |
| spellingShingle | E. V. Yani E. N. Iomdina V. V. Pozdniakova V. A. Golikova K. E. Seliverstova Treating protracted corneal ulcers with UVA corneal collagen crosslinking: clinical cases Российский офтальмологический журнал corneal ulcer treatment ultraviolet crosslinking device for local corneal collagen crosslinking |
| title | Treating protracted corneal ulcers with UVA corneal collagen crosslinking: clinical cases |
| title_full | Treating protracted corneal ulcers with UVA corneal collagen crosslinking: clinical cases |
| title_fullStr | Treating protracted corneal ulcers with UVA corneal collagen crosslinking: clinical cases |
| title_full_unstemmed | Treating protracted corneal ulcers with UVA corneal collagen crosslinking: clinical cases |
| title_short | Treating protracted corneal ulcers with UVA corneal collagen crosslinking: clinical cases |
| title_sort | treating protracted corneal ulcers with uva corneal collagen crosslinking clinical cases |
| topic | corneal ulcer treatment ultraviolet crosslinking device for local corneal collagen crosslinking |
| url | https://roj.igb.ru/jour/article/view/729 |
| work_keys_str_mv | AT evyani treatingprotractedcornealulcerswithuvacornealcollagencrosslinkingclinicalcases AT eniomdina treatingprotractedcornealulcerswithuvacornealcollagencrosslinkingclinicalcases AT vvpozdniakova treatingprotractedcornealulcerswithuvacornealcollagencrosslinkingclinicalcases AT vagolikova treatingprotractedcornealulcerswithuvacornealcollagencrosslinkingclinicalcases AT keseliverstova treatingprotractedcornealulcerswithuvacornealcollagencrosslinkingclinicalcases |