Durable immunotherapeutic response in molecularly complex pulmonary adenosquamous carcinoma: case report and literature review

Durable immunotherapeutic response in molecularly complex pulmonary adenosquamous carcinoma: case report and literature review

Pulmonary adenosquamous carcinoma (ASC) is a rare and aggressive subtype of non-small cell lung cancer (NSCLC) with poorly defined molecular characteristics and therapeutic strategies. We present a 63-year-old male patient with stage IVa (cT4N3M1b) lung ASC. Next-generation sequencing (NGS) revealed...

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Bibliographic Details
Main Authors:	Jun Zhu, Xin Xun, Jiayun Liu, Bin Su, Yi Li, Hong Chen, Meijin Huang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Series:	Frontiers in Immunology
Subjects:	non-small cell lung cancer (NSCLC) lung adenosquamous carcinoma immune checkpoint inhibitors (ICIs) immunotherapy gene mutation
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1614283/full
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