Nanoparticles and female reproductive toxicity: A review
This review gives relevant introductory information on nanoparticles, their properties and applica-tions in different fields. Nanotechnology today has expanded and evolved in almost every field and includes application in electronics, sensing, detection, catalysis, and biomedical sciences. Due to an...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Faculty of Veterinary Medicine, Trakia University, Stara Zagora, Bulgaria
2025-09-01
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| Series: | Bulgarian Journal of Veterinary Medicine |
| Subjects: | |
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| Summary: | This review gives relevant introductory information on nanoparticles, their properties and applica-tions in different fields. Nanotechnology today has expanded and evolved in almost every field and includes application in electronics, sensing, detection, catalysis, and biomedical sciences. Due to anthropogenic methods of nanoparticles synthesis, the applications have increased dramatically within the last century. This increase in consumption has led to increase in potential toxicity of nanoparticles especially in reproductive system. Nanoparticles have the potential to cross some bio-logical membranes and accumulate in the reproductive system after translocating from the circulatory and lymphatic systems. NPs can enter the ovaries and interfere with normal ovarian functions like synthesis of sex steroid hormones, shape and functions of ovarian cells, impairment of follicular de-velopment and oocyte quality. Their ability to effect uterine epithelial cells cannot be ignored. Nu-merous studies have shown that an abnormal redox balance mediated by reactive oxygen species pro-duction and activation and inactivation of apoptotic and anti-apoptotic factors within cells are key factors in NP-induced toxicity. This review tries to provide enhanced understanding about the NPs and female reproductive toxicity that may become helpful in creating mitigation techniques for safe applications of nanoparticles in humans. |
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| ISSN: | 1311-1477 1313-3543 |