Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study
<i>Background and Objectives</i>: Complex wounds in the hand and distal lower extremities pose challenges in reconstructive surgery, often involving critical structures like tendons. Tendon injuries, prevalent in such wounds, necessitate optimal repair methods for functional recovery. Th...
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2024-10-01
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| author | Mehmet Yucens Ahmet Nadir Aydemir Tarık Sengoz Gulcin Abban Mete Nusret Ök Mehmet Rauf Koç Ahmet Fahir Demirkan |
| author_facet | Mehmet Yucens Ahmet Nadir Aydemir Tarık Sengoz Gulcin Abban Mete Nusret Ök Mehmet Rauf Koç Ahmet Fahir Demirkan |
| author_sort | Mehmet Yucens |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Complex wounds in the hand and distal lower extremities pose challenges in reconstructive surgery, often involving critical structures like tendons. Tendon injuries, prevalent in such wounds, necessitate optimal repair methods for functional recovery. This study investigates the impact of vascularised and nonvascularised adipofascial tissue on tendon repair, focusing on early healing stages, mobilisation, and scintigraphic evaluation of flap vascularity. <i>Materials and Methods:</i> Wistar Albino rats were divided into groups undergoing primary tendon repair, vascularised adipofascial flap application, or nonvascularised flap application. Scintigraphic evaluation and histopathological assessment were performed to analyse healing processes. <i>Results</i>: Pedicle-free flaps support healing in tendon injuries without negatively affecting medium-term outcomes. Vascularised flaps exhibit faster healing. The scintigraphic analysis showed that the static measurements of the late phase were statistically significantly higher in the group with the non-vascularised adipofascial flap (<i>p</i> = 0.038). The mean perfusion reserve was higher in the vascularised pedicled adipofascial flap group than the non-vascularised adipofascial flap group. Scintigraphic analysis highlights the viability of pedicle-free flaps. <i>Conclusions</i>: Pedicle-free adipofascial flaps support the healing of the tendon without complicating the results, while vascularised flaps show accelerated healing. These findings provide valuable insights into optimising tendon repair strategies using adipofascial flaps, with implications for enhancing functional recovery in complex wounds. |
| format | Article |
| id | doaj-art-85b65ae4e063406ebc010f0fd6f81137 |
| institution | OA Journals |
| issn | 1010-660X 1648-9144 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj-art-85b65ae4e063406ebc010f0fd6f811372025-08-20T02:10:56ZengMDPI AGMedicina1010-660X1648-91442024-10-016010168910.3390/medicina60101689Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model StudyMehmet Yucens0Ahmet Nadir Aydemir1Tarık Sengoz2Gulcin Abban Mete3Nusret Ök4Mehmet Rauf Koç5Ahmet Fahir Demirkan6Faculty Depth of Orthopaedics, Pamukkale University Medicine, Denizli 20160, TurkeyFaculty Depth of Orthopaedics, Pamukkale University Medicine, Denizli 20160, TurkeyFaculty Depth of Nucleer Medicine, Pamukkale University Medicine, Denizli 20160, TurkeyFaculty Depth of Histology, Pamukakle University Medicine, Denizli 20160, TurkeyFaculty Depth of Orthopaedics, Pamukkale University Medicine, Denizli 20160, Turkeyİzmir City Hospital, İzmir 35510, TurkeyFaculty Depth of Orthopaedics, Pamukkale University Medicine, Denizli 20160, Turkey<i>Background and Objectives</i>: Complex wounds in the hand and distal lower extremities pose challenges in reconstructive surgery, often involving critical structures like tendons. Tendon injuries, prevalent in such wounds, necessitate optimal repair methods for functional recovery. This study investigates the impact of vascularised and nonvascularised adipofascial tissue on tendon repair, focusing on early healing stages, mobilisation, and scintigraphic evaluation of flap vascularity. <i>Materials and Methods:</i> Wistar Albino rats were divided into groups undergoing primary tendon repair, vascularised adipofascial flap application, or nonvascularised flap application. Scintigraphic evaluation and histopathological assessment were performed to analyse healing processes. <i>Results</i>: Pedicle-free flaps support healing in tendon injuries without negatively affecting medium-term outcomes. Vascularised flaps exhibit faster healing. The scintigraphic analysis showed that the static measurements of the late phase were statistically significantly higher in the group with the non-vascularised adipofascial flap (<i>p</i> = 0.038). The mean perfusion reserve was higher in the vascularised pedicled adipofascial flap group than the non-vascularised adipofascial flap group. Scintigraphic analysis highlights the viability of pedicle-free flaps. <i>Conclusions</i>: Pedicle-free adipofascial flaps support the healing of the tendon without complicating the results, while vascularised flaps show accelerated healing. These findings provide valuable insights into optimising tendon repair strategies using adipofascial flaps, with implications for enhancing functional recovery in complex wounds.https://www.mdpi.com/1648-9144/60/10/1689tendon repairadipofascial flapsvascularised flapsnon-vascularised flapsscintigraphyhistopathology |
| spellingShingle | Mehmet Yucens Ahmet Nadir Aydemir Tarık Sengoz Gulcin Abban Mete Nusret Ök Mehmet Rauf Koç Ahmet Fahir Demirkan Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study Medicina tendon repair adipofascial flaps vascularised flaps non-vascularised flaps scintigraphy histopathology |
| title | Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study |
| title_full | Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study |
| title_fullStr | Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study |
| title_full_unstemmed | Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study |
| title_short | Vascularised and Non-Vascularised Adipofascial Flap Applications in Tissue Trauma with Tendon Injury, Flap Viability and Tendon Healing a Hystological and Scintigraphical Rat Model Study |
| title_sort | vascularised and non vascularised adipofascial flap applications in tissue trauma with tendon injury flap viability and tendon healing a hystological and scintigraphical rat model study |
| topic | tendon repair adipofascial flaps vascularised flaps non-vascularised flaps scintigraphy histopathology |
| url | https://www.mdpi.com/1648-9144/60/10/1689 |
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