Bioimaging comparison between synthesized carbon quantum dots and nanodiamonds
Objective(s): Scientists have been focused on finding access to the potential of different materials, incredibly natural substances. This work compared two categories of nanoscale materials based on carbon sources, including carbon quantum dots (C-QDs) and detonation nanodiamonds (DNDs). Materials a...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Mashhad University of Medical Sciences
2025-07-01
|
| Series: | Nanomedicine Journal |
| Subjects: | |
| Online Access: | https://nmj.mums.ac.ir/article_25565_a2e3e8f949df0171ce5b658a8b728336.pdf |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849731029022015488 |
|---|---|
| author | Somayeh Marouzi Shirin Sammak Kayvan Sadri Majid Darroudi |
| author_facet | Somayeh Marouzi Shirin Sammak Kayvan Sadri Majid Darroudi |
| author_sort | Somayeh Marouzi |
| collection | DOAJ |
| description | Objective(s): Scientists have been focused on finding access to the potential of different materials, incredibly natural substances. This work compared two categories of nanoscale materials based on carbon sources, including carbon quantum dots (C-QDs) and detonation nanodiamonds (DNDs). Materials and Methods: The hydrothermally synthesized C-QDs from Salvia Hispanic L. and DNDs were compared through physicochemical tests such as ultra-violet spectrophotometry (UV-Vis), Fourier transform infrared (FT-IR), X-ray diffraction (XRD), and field emission scanning microscopy (FESEM). Then, we investigated their cytotoxicity and biocompatibility on HEK293 and HepG2 cell lines, respectively. To focus on nanoparticle biodistribution and shelf life throughout the in vivo studies of rats, C-QDs and DNDs were labeled by Technetium (99mTc) radioisotope for tracking purposes. Results: The characterization and cytotoxicity outcomes of C-QDs and DNDs confirmed both cases' relative intrinsic similarity and non-toxicity, which also gained permission to enter the in vivo studies of rats.Conclusion: According to biodistribution assessments, despite the slight differences between their biological properties, C-QDs, and DNDs exhibited different bioaccumulation tendencies toward organ selection. |
| format | Article |
| id | doaj-art-85b4ea9c09584bf8acb8eb6e30dbc491 |
| institution | DOAJ |
| issn | 2322-3049 2322-5904 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Nanomedicine Journal |
| spelling | doaj-art-85b4ea9c09584bf8acb8eb6e30dbc4912025-08-20T03:08:40ZengMashhad University of Medical SciencesNanomedicine Journal2322-30492322-59042025-07-0112352954510.22038/nmj.2025.81851.203725565Bioimaging comparison between synthesized carbon quantum dots and nanodiamondsSomayeh Marouzi0Shirin Sammak1Kayvan Sadri2Majid Darroudi3Department of Pharmaceutical Biotechnology, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, IranDepartment of Medical Biotechnology and Nanotechnology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, IranNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, IranNuclear Medicine Research Center, Mashhad University of Medical Sciences, Mashhad, IranObjective(s): Scientists have been focused on finding access to the potential of different materials, incredibly natural substances. This work compared two categories of nanoscale materials based on carbon sources, including carbon quantum dots (C-QDs) and detonation nanodiamonds (DNDs). Materials and Methods: The hydrothermally synthesized C-QDs from Salvia Hispanic L. and DNDs were compared through physicochemical tests such as ultra-violet spectrophotometry (UV-Vis), Fourier transform infrared (FT-IR), X-ray diffraction (XRD), and field emission scanning microscopy (FESEM). Then, we investigated their cytotoxicity and biocompatibility on HEK293 and HepG2 cell lines, respectively. To focus on nanoparticle biodistribution and shelf life throughout the in vivo studies of rats, C-QDs and DNDs were labeled by Technetium (99mTc) radioisotope for tracking purposes. Results: The characterization and cytotoxicity outcomes of C-QDs and DNDs confirmed both cases' relative intrinsic similarity and non-toxicity, which also gained permission to enter the in vivo studies of rats.Conclusion: According to biodistribution assessments, despite the slight differences between their biological properties, C-QDs, and DNDs exhibited different bioaccumulation tendencies toward organ selection.https://nmj.mums.ac.ir/article_25565_a2e3e8f949df0171ce5b658a8b728336.pdfcarbon quantum dotstechnetiumnanodiamondshydrothermal synthesisbioimaging |
| spellingShingle | Somayeh Marouzi Shirin Sammak Kayvan Sadri Majid Darroudi Bioimaging comparison between synthesized carbon quantum dots and nanodiamonds Nanomedicine Journal carbon quantum dots technetium nanodiamonds hydrothermal synthesis bioimaging |
| title | Bioimaging comparison between synthesized carbon quantum dots and nanodiamonds |
| title_full | Bioimaging comparison between synthesized carbon quantum dots and nanodiamonds |
| title_fullStr | Bioimaging comparison between synthesized carbon quantum dots and nanodiamonds |
| title_full_unstemmed | Bioimaging comparison between synthesized carbon quantum dots and nanodiamonds |
| title_short | Bioimaging comparison between synthesized carbon quantum dots and nanodiamonds |
| title_sort | bioimaging comparison between synthesized carbon quantum dots and nanodiamonds |
| topic | carbon quantum dots technetium nanodiamonds hydrothermal synthesis bioimaging |
| url | https://nmj.mums.ac.ir/article_25565_a2e3e8f949df0171ce5b658a8b728336.pdf |
| work_keys_str_mv | AT somayehmarouzi bioimagingcomparisonbetweensynthesizedcarbonquantumdotsandnanodiamonds AT shirinsammak bioimagingcomparisonbetweensynthesizedcarbonquantumdotsandnanodiamonds AT kayvansadri bioimagingcomparisonbetweensynthesizedcarbonquantumdotsandnanodiamonds AT majiddarroudi bioimagingcomparisonbetweensynthesizedcarbonquantumdotsandnanodiamonds |