Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma
Occult hepatitis B (OBI) is caused by a persistent low-level replication of HBV. Like overt HBV infection, OBI can be associated with the integration of HBV sequences into the host genome and has a substantial clinical relevance for patients who are severely immunosuppressed for long durations. We p...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | Case Reports in Hematology |
| Online Access: | http://dx.doi.org/10.1155/2012/803298 |
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| _version_ | 1832548617707061248 |
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| author | Vincenzo Pitini Massimo Rizzo Carmela Arrigo Patrizia Mondello Giuseppe Altavilla |
| author_facet | Vincenzo Pitini Massimo Rizzo Carmela Arrigo Patrizia Mondello Giuseppe Altavilla |
| author_sort | Vincenzo Pitini |
| collection | DOAJ |
| description | Occult hepatitis B (OBI) is caused by a persistent low-level replication of HBV. Like overt HBV infection, OBI can be associated with the integration of HBV sequences into the host genome and has a substantial clinical relevance for patients who are severely immunosuppressed for long durations. We present the case of a patient with a diffuse large B-cell non-Hodgkin lymphoma and OBI who developed a hepatocellular carcinoma with a fulminant clinical course following the administration of rituximab plus CHOP. |
| format | Article |
| id | doaj-art-85aead0d5334423e8277242dd4a8b07c |
| institution | Kabale University |
| issn | 2090-6560 2090-6579 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Hematology |
| spelling | doaj-art-85aead0d5334423e8277242dd4a8b07c2025-02-03T06:13:37ZengWileyCase Reports in Hematology2090-65602090-65792012-01-01201210.1155/2012/803298803298Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell LymphomaVincenzo Pitini0Massimo Rizzo1Carmela Arrigo2Patrizia Mondello3Giuseppe Altavilla4Department of Medical Oncology (Pad. H 5° Piano), University of Messina, Via Consolare Valeria Road 98125 Messina, ItalyDepartment of Medical Oncology (Pad. H 5° Piano), University of Messina, Via Consolare Valeria Road 98125 Messina, ItalyDepartment of Medical Oncology (Pad. H 5° Piano), University of Messina, Via Consolare Valeria Road 98125 Messina, ItalyDepartment of Medical Oncology (Pad. H 5° Piano), University of Messina, Via Consolare Valeria Road 98125 Messina, ItalyDepartment of Medical Oncology (Pad. H 5° Piano), University of Messina, Via Consolare Valeria Road 98125 Messina, ItalyOccult hepatitis B (OBI) is caused by a persistent low-level replication of HBV. Like overt HBV infection, OBI can be associated with the integration of HBV sequences into the host genome and has a substantial clinical relevance for patients who are severely immunosuppressed for long durations. We present the case of a patient with a diffuse large B-cell non-Hodgkin lymphoma and OBI who developed a hepatocellular carcinoma with a fulminant clinical course following the administration of rituximab plus CHOP.http://dx.doi.org/10.1155/2012/803298 |
| spellingShingle | Vincenzo Pitini Massimo Rizzo Carmela Arrigo Patrizia Mondello Giuseppe Altavilla Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma Case Reports in Hematology |
| title | Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma |
| title_full | Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma |
| title_fullStr | Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma |
| title_full_unstemmed | Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma |
| title_short | Fatal Hepatocellular Carcinoma in a Patient with Occult Hepatitis B Virus Infection following the Administration of R-CHOP for Diffuse Large B-Cell Lymphoma |
| title_sort | fatal hepatocellular carcinoma in a patient with occult hepatitis b virus infection following the administration of r chop for diffuse large b cell lymphoma |
| url | http://dx.doi.org/10.1155/2012/803298 |
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