Environmental arsenic hijacks DDX5-mediated FANCA splicing to impair R-loops resolution and drive ovarian aging
Arsenic, a widespread environmental toxicant, is increasingly implicated in female reproductive dysfunction. Long-term exposure to low concentrations of arsenic leads to diminished ovarian reserve. However, the mechanisms by which arsenic exposure accelerates ovarian aging remain unclear. Here, we d...
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| Main Authors: | Tuo Zhang, Jin Niu, Lu Yang, Yuanyuan Yu, Meina He, Changfa Wu, Zengmei Cheng, Mei Pan, Zerui Hong, Jian Sun, Yuan Gao, Tengxiang Chen, Zhengrong Wang, Wei Pan |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2025-09-01
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| Series: | Ecotoxicology and Environmental Safety |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0147651325009509 |
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