Effectiveness of radiofrequency renal denervation in diseases with increased sympathetic nervous system activity

The article discusses the role of sympathetic nervous system hyperactivity in the pathogenesis of various pathologies (hypertension, heart failure, atrial fibrillation, metabolic syndrome, diabetes and systemic inflammatory response syndrome). On the example of large randomized clinical trials using...

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Main Authors: B. A. Rudenko, D. A. Feshchenko, D. K. Vasiliev, F. B. Shukurov, A. S. Shanoyan, M. N. Mamedov, O. M. Drapkina
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2022-01-01
Series:Кардиоваскулярная терапия и профилактика
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Online Access:https://cardiovascular.elpub.ru/jour/article/view/3139
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author B. A. Rudenko
D. A. Feshchenko
D. K. Vasiliev
F. B. Shukurov
A. S. Shanoyan
M. N. Mamedov
O. M. Drapkina
author_facet B. A. Rudenko
D. A. Feshchenko
D. K. Vasiliev
F. B. Shukurov
A. S. Shanoyan
M. N. Mamedov
O. M. Drapkina
author_sort B. A. Rudenko
collection DOAJ
description The article discusses the role of sympathetic nervous system hyperactivity in the pathogenesis of various pathologies (hypertension, heart failure, atrial fibrillation, metabolic syndrome, diabetes and systemic inflammatory response syndrome). On the example of large randomized clinical trials using catheter-based radiofrequency ablation, the antihypertensive effect in patients with uncontrolled hypertension has been proven. The first experimental and clinical studies on the effectiveness of renal denervation in reducing the activity of inflammatory markers, the incidence of atrial fibrillation and ventricular arrhythmia episodes, and improving the left ventricular contractility. The first clinical results of the favorable effect of renal denervation on carbohydrate metabolism (insulin resistance and glycemic level) in patients with metabolic syndrome and diabetes have been studied in detail.
format Article
id doaj-art-8586fa37cf154ed3967ef91ad6c0c9fb
institution DOAJ
issn 1728-8800
2619-0125
language Russian
publishDate 2022-01-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-8586fa37cf154ed3967ef91ad6c0c9fb2025-08-20T03:18:46Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252022-01-0120810.15829/1728-8800-2021-31392400Effectiveness of radiofrequency renal denervation in diseases with increased sympathetic nervous system activityB. A. Rudenko0D. A. Feshchenko1D. K. Vasiliev2F. B. Shukurov3A. S. Shanoyan4M. N. Mamedov5O. M. Drapkina6National Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineNational Medical Research Center for Therapy and Preventive MedicineThe article discusses the role of sympathetic nervous system hyperactivity in the pathogenesis of various pathologies (hypertension, heart failure, atrial fibrillation, metabolic syndrome, diabetes and systemic inflammatory response syndrome). On the example of large randomized clinical trials using catheter-based radiofrequency ablation, the antihypertensive effect in patients with uncontrolled hypertension has been proven. The first experimental and clinical studies on the effectiveness of renal denervation in reducing the activity of inflammatory markers, the incidence of atrial fibrillation and ventricular arrhythmia episodes, and improving the left ventricular contractility. The first clinical results of the favorable effect of renal denervation on carbohydrate metabolism (insulin resistance and glycemic level) in patients with metabolic syndrome and diabetes have been studied in detail.https://cardiovascular.elpub.ru/jour/article/view/3139hypertensionradiofrequency ablationrenal denervationdiabetessympathetic hyperactivity
spellingShingle B. A. Rudenko
D. A. Feshchenko
D. K. Vasiliev
F. B. Shukurov
A. S. Shanoyan
M. N. Mamedov
O. M. Drapkina
Effectiveness of radiofrequency renal denervation in diseases with increased sympathetic nervous system activity
Кардиоваскулярная терапия и профилактика
hypertension
radiofrequency ablation
renal denervation
diabetes
sympathetic hyperactivity
title Effectiveness of radiofrequency renal denervation in diseases with increased sympathetic nervous system activity
title_full Effectiveness of radiofrequency renal denervation in diseases with increased sympathetic nervous system activity
title_fullStr Effectiveness of radiofrequency renal denervation in diseases with increased sympathetic nervous system activity
title_full_unstemmed Effectiveness of radiofrequency renal denervation in diseases with increased sympathetic nervous system activity
title_short Effectiveness of radiofrequency renal denervation in diseases with increased sympathetic nervous system activity
title_sort effectiveness of radiofrequency renal denervation in diseases with increased sympathetic nervous system activity
topic hypertension
radiofrequency ablation
renal denervation
diabetes
sympathetic hyperactivity
url https://cardiovascular.elpub.ru/jour/article/view/3139
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AT fbshukurov effectivenessofradiofrequencyrenaldenervationindiseaseswithincreasedsympatheticnervoussystemactivity
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