Electrochemical Analysis of Rationally Designed ZnO Nanostructures for Biodegradable Cellular Scaffolds

This work is a preliminary analysis of a wet-chemistry synthesized platform based on ZnO nanostructures (n-ZnO) for application in regenerative medicine. n-ZnO stability is investigated by electrochemical in situ sensing of zinc ions released by n-ZnO soaked in simulated biofluids. Impedance analysi...

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Main Authors: Giuseppe Arrabito, Vittorio Ferrara, Giuseppe Prestopino, Pier Gianni Medaglia, Michelangelo Scopelliti, Bruno Pignataro
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Proceedings
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Online Access:https://www.mdpi.com/2504-3900/97/1/212
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author Giuseppe Arrabito
Vittorio Ferrara
Giuseppe Prestopino
Pier Gianni Medaglia
Michelangelo Scopelliti
Bruno Pignataro
author_facet Giuseppe Arrabito
Vittorio Ferrara
Giuseppe Prestopino
Pier Gianni Medaglia
Michelangelo Scopelliti
Bruno Pignataro
author_sort Giuseppe Arrabito
collection DOAJ
description This work is a preliminary analysis of a wet-chemistry synthesized platform based on ZnO nanostructures (n-ZnO) for application in regenerative medicine. n-ZnO stability is investigated by electrochemical in situ sensing of zinc ions released by n-ZnO soaked in simulated biofluids. Impedance analysis allows detection of subtle changes in the bulk solution impedance up to 50 kHz, which can be ascribed to the release of ionic species in solution, among which are Zn<sup>2+</sup> ions. In parallel, a voltammetry analysis using low-cost, mercury-free, screen-printed sensors shows the release of Zn<sup>2+</sup> ions at concentrations that are not harmful.
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id doaj-art-858240743bf440f5a0c7dcd1fe2d2111
institution DOAJ
issn 2504-3900
language English
publishDate 2024-05-01
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spelling doaj-art-858240743bf440f5a0c7dcd1fe2d21112025-08-20T02:57:04ZengMDPI AGProceedings2504-39002024-05-0197121210.3390/proceedings2024097212Electrochemical Analysis of Rationally Designed ZnO Nanostructures for Biodegradable Cellular ScaffoldsGiuseppe Arrabito0Vittorio Ferrara1Giuseppe Prestopino2Pier Gianni Medaglia3Michelangelo Scopelliti4Bruno Pignataro5Department of Physics and Chemistry—Emilio Segrè, University of Palermo, Viale delle Scienze 17, 90128 Palermo, ItalyDepartment of Physics and Chemistry—Emilio Segrè, University of Palermo, Viale delle Scienze 17, 90128 Palermo, ItalyDepartment of Industrial Engineering, University of Rome “Tor Vergata”, Via del Politecnico 1, 00133 Rome, ItalyDepartment of Industrial Engineering, University of Rome “Tor Vergata”, Via del Politecnico 1, 00133 Rome, ItalyDepartment of Physics and Chemistry—Emilio Segrè, University of Palermo, Viale delle Scienze 17, 90128 Palermo, ItalyDepartment of Physics and Chemistry—Emilio Segrè, University of Palermo, Viale delle Scienze 17, 90128 Palermo, ItalyThis work is a preliminary analysis of a wet-chemistry synthesized platform based on ZnO nanostructures (n-ZnO) for application in regenerative medicine. n-ZnO stability is investigated by electrochemical in situ sensing of zinc ions released by n-ZnO soaked in simulated biofluids. Impedance analysis allows detection of subtle changes in the bulk solution impedance up to 50 kHz, which can be ascribed to the release of ionic species in solution, among which are Zn<sup>2+</sup> ions. In parallel, a voltammetry analysis using low-cost, mercury-free, screen-printed sensors shows the release of Zn<sup>2+</sup> ions at concentrations that are not harmful.https://www.mdpi.com/2504-3900/97/1/212ZnO nanostructuresmetal oxide crystalsimpedancezinc ion determination
spellingShingle Giuseppe Arrabito
Vittorio Ferrara
Giuseppe Prestopino
Pier Gianni Medaglia
Michelangelo Scopelliti
Bruno Pignataro
Electrochemical Analysis of Rationally Designed ZnO Nanostructures for Biodegradable Cellular Scaffolds
Proceedings
ZnO nanostructures
metal oxide crystals
impedance
zinc ion determination
title Electrochemical Analysis of Rationally Designed ZnO Nanostructures for Biodegradable Cellular Scaffolds
title_full Electrochemical Analysis of Rationally Designed ZnO Nanostructures for Biodegradable Cellular Scaffolds
title_fullStr Electrochemical Analysis of Rationally Designed ZnO Nanostructures for Biodegradable Cellular Scaffolds
title_full_unstemmed Electrochemical Analysis of Rationally Designed ZnO Nanostructures for Biodegradable Cellular Scaffolds
title_short Electrochemical Analysis of Rationally Designed ZnO Nanostructures for Biodegradable Cellular Scaffolds
title_sort electrochemical analysis of rationally designed zno nanostructures for biodegradable cellular scaffolds
topic ZnO nanostructures
metal oxide crystals
impedance
zinc ion determination
url https://www.mdpi.com/2504-3900/97/1/212
work_keys_str_mv AT giuseppearrabito electrochemicalanalysisofrationallydesignedznonanostructuresforbiodegradablecellularscaffolds
AT vittorioferrara electrochemicalanalysisofrationallydesignedznonanostructuresforbiodegradablecellularscaffolds
AT giuseppeprestopino electrochemicalanalysisofrationallydesignedznonanostructuresforbiodegradablecellularscaffolds
AT piergiannimedaglia electrochemicalanalysisofrationallydesignedznonanostructuresforbiodegradablecellularscaffolds
AT michelangeloscopelliti electrochemicalanalysisofrationallydesignedznonanostructuresforbiodegradablecellularscaffolds
AT brunopignataro electrochemicalanalysisofrationallydesignedznonanostructuresforbiodegradablecellularscaffolds