Electrochemical Analysis of Rationally Designed ZnO Nanostructures for Biodegradable Cellular Scaffolds

This work is a preliminary analysis of a wet-chemistry synthesized platform based on ZnO nanostructures (n-ZnO) for application in regenerative medicine. n-ZnO stability is investigated by electrochemical in situ sensing of zinc ions released by n-ZnO soaked in simulated biofluids. Impedance analysi...

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Bibliographic Details
Main Authors: Giuseppe Arrabito, Vittorio Ferrara, Giuseppe Prestopino, Pier Gianni Medaglia, Michelangelo Scopelliti, Bruno Pignataro
Format: Article
Language:English
Published: MDPI AG 2024-05-01
Series:Proceedings
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Online Access:https://www.mdpi.com/2504-3900/97/1/212
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Summary:This work is a preliminary analysis of a wet-chemistry synthesized platform based on ZnO nanostructures (n-ZnO) for application in regenerative medicine. n-ZnO stability is investigated by electrochemical in situ sensing of zinc ions released by n-ZnO soaked in simulated biofluids. Impedance analysis allows detection of subtle changes in the bulk solution impedance up to 50 kHz, which can be ascribed to the release of ionic species in solution, among which are Zn<sup>2+</sup> ions. In parallel, a voltammetry analysis using low-cost, mercury-free, screen-printed sensors shows the release of Zn<sup>2+</sup> ions at concentrations that are not harmful.
ISSN:2504-3900