Innovative strategies for organophosphorus remediation: Integrating enzymatic decomposition with membrane technologies
Organophosphorus (OP) compounds, widely used in agriculture, pharmaceuticals, and flame retardancy, pose significant environmental and health risks due to their toxicity, particularly neurotoxicity. While enzymatic degradation and membrane technologies have been studied separately for OP remediation...
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| Language: | English |
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Elsevier
2025-05-01
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| Series: | Results in Chemistry |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715625002814 |
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| author | Morteza Mirzaei Ramezan Ali Taheri Ali Mohammad Latifi Majid Abdouss |
| author_facet | Morteza Mirzaei Ramezan Ali Taheri Ali Mohammad Latifi Majid Abdouss |
| author_sort | Morteza Mirzaei |
| collection | DOAJ |
| description | Organophosphorus (OP) compounds, widely used in agriculture, pharmaceuticals, and flame retardancy, pose significant environmental and health risks due to their toxicity, particularly neurotoxicity. While enzymatic degradation and membrane technologies have been studied separately for OP remediation, there is a lack of comprehensive research on the synergistic integration of enzyme-based catalysis with membrane systems. This review addresses this gap by analyzing how enzyme immobilization onto membrane supports enhances the efficiency, stability, and reusability of organophosphorus (OP) degradation processes. We compare various enzyme immobilization strategies (adsorption, covalent bonding, crosslinking) and assess their respective benefits and challenges. Additionally, we introduce a new framework aligning membrane-supported enzyme systems with specific OP decomposition challenges, such as enzyme deactivation and improving continuous-flow performance. Furthermore, this review highlights emerging trends, such as the integration of nanostructured materials like metal-organic frameworks (MOFs) and carbon nanotubes (CNTs) into membranes. These hybrid systems enhance catalytic degradation and offer filtration capabilities, providing a dual advantage over free enzymes or powdered nanomaterials. Enzyme-based membranes enhance enzyme stability, reusability, and operational convenience—particularly in continuous-flow systems—while also capturing particulate contaminants. By exploring enzyme–MOF–membrane composites, we propose innovative solutions for OP remediation in civilian and military applications. This work presents innovative perspectives on enzyme-based membrane technologies, offering efficient, scalable, and environmentally sustainable methods for OP detoxification. Future research should focus on developing integrated, real-time monitoring technologies to further enhance the practicality and scalability of these systems. |
| format | Article |
| id | doaj-art-8578dcf6327f4c53a9aabfb5627cfdcc |
| institution | OA Journals |
| issn | 2211-7156 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Results in Chemistry |
| spelling | doaj-art-8578dcf6327f4c53a9aabfb5627cfdcc2025-08-20T02:09:05ZengElsevierResults in Chemistry2211-71562025-05-011510229810.1016/j.rechem.2025.102298Innovative strategies for organophosphorus remediation: Integrating enzymatic decomposition with membrane technologiesMorteza Mirzaei0Ramezan Ali Taheri1Ali Mohammad Latifi2Majid Abdouss3Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran; Corresponding authors.Nanobiotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IranApplied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, Tehran, IranDepartment of Chemistry, Amirkabir University of Technology, Tehran, Iran; Corresponding authors.Organophosphorus (OP) compounds, widely used in agriculture, pharmaceuticals, and flame retardancy, pose significant environmental and health risks due to their toxicity, particularly neurotoxicity. While enzymatic degradation and membrane technologies have been studied separately for OP remediation, there is a lack of comprehensive research on the synergistic integration of enzyme-based catalysis with membrane systems. This review addresses this gap by analyzing how enzyme immobilization onto membrane supports enhances the efficiency, stability, and reusability of organophosphorus (OP) degradation processes. We compare various enzyme immobilization strategies (adsorption, covalent bonding, crosslinking) and assess their respective benefits and challenges. Additionally, we introduce a new framework aligning membrane-supported enzyme systems with specific OP decomposition challenges, such as enzyme deactivation and improving continuous-flow performance. Furthermore, this review highlights emerging trends, such as the integration of nanostructured materials like metal-organic frameworks (MOFs) and carbon nanotubes (CNTs) into membranes. These hybrid systems enhance catalytic degradation and offer filtration capabilities, providing a dual advantage over free enzymes or powdered nanomaterials. Enzyme-based membranes enhance enzyme stability, reusability, and operational convenience—particularly in continuous-flow systems—while also capturing particulate contaminants. By exploring enzyme–MOF–membrane composites, we propose innovative solutions for OP remediation in civilian and military applications. This work presents innovative perspectives on enzyme-based membrane technologies, offering efficient, scalable, and environmentally sustainable methods for OP detoxification. Future research should focus on developing integrated, real-time monitoring technologies to further enhance the practicality and scalability of these systems.http://www.sciencedirect.com/science/article/pii/S2211715625002814OrganophosphorusEnzymatic degradationBioremediationEnzyme immobilizationMembrane technologyEnvironmental remediation |
| spellingShingle | Morteza Mirzaei Ramezan Ali Taheri Ali Mohammad Latifi Majid Abdouss Innovative strategies for organophosphorus remediation: Integrating enzymatic decomposition with membrane technologies Results in Chemistry Organophosphorus Enzymatic degradation Bioremediation Enzyme immobilization Membrane technology Environmental remediation |
| title | Innovative strategies for organophosphorus remediation: Integrating enzymatic decomposition with membrane technologies |
| title_full | Innovative strategies for organophosphorus remediation: Integrating enzymatic decomposition with membrane technologies |
| title_fullStr | Innovative strategies for organophosphorus remediation: Integrating enzymatic decomposition with membrane technologies |
| title_full_unstemmed | Innovative strategies for organophosphorus remediation: Integrating enzymatic decomposition with membrane technologies |
| title_short | Innovative strategies for organophosphorus remediation: Integrating enzymatic decomposition with membrane technologies |
| title_sort | innovative strategies for organophosphorus remediation integrating enzymatic decomposition with membrane technologies |
| topic | Organophosphorus Enzymatic degradation Bioremediation Enzyme immobilization Membrane technology Environmental remediation |
| url | http://www.sciencedirect.com/science/article/pii/S2211715625002814 |
| work_keys_str_mv | AT mortezamirzaei innovativestrategiesfororganophosphorusremediationintegratingenzymaticdecompositionwithmembranetechnologies AT ramezanalitaheri innovativestrategiesfororganophosphorusremediationintegratingenzymaticdecompositionwithmembranetechnologies AT alimohammadlatifi innovativestrategiesfororganophosphorusremediationintegratingenzymaticdecompositionwithmembranetechnologies AT majidabdouss innovativestrategiesfororganophosphorusremediationintegratingenzymaticdecompositionwithmembranetechnologies |