The efficacy of immunotherapy in non-small cell lung cancer with KRAS mutation: a systematic review and meta-analysis

The efficacy of immunotherapy in non-small cell lung cancer with KRAS mutation: a systematic review and meta-analysis

Abstract Purpose The KRAS mutation is highly prevalent in NSCLC and is associated with poor efficacy of immunotherapy. Nevertheless, the impact of KRAS mutation, mutation subtypes, and co-mutations on the effectiveness of immunotherapy remains uncertain. This study aimed to assess the influence of t...

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Bibliographic Details
Main Authors: Rui Zhao, Yang Shu, Wei Xu, Fengxian Jiang, Pancen Ran, Liying Pan, Jingliang Wang, Weihao Wang, Jing Zhao, Yahui Wang, Guobin Fu
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Cancer Cell International
Subjects:
KRAS mutation
KRAS mutation subtype
KRAS co-mutation
Immunotherapy
NSCLC
Meta-analysis
Online Access:https://doi.org/10.1186/s12935-024-03498-9
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